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观察IL-10在H.pylori相关性胃炎组织中的表达及与COX-2、iNOS的相关性。方法:选取74例H.pylori相关性胃炎患者，均行H.pylori检测确定H.pylori感染情况，行病理组织学检测明确病理分型、胃黏膜炎症程度，行免疫组化检测胃黏膜中IL-10、COX-2、iNOS表达。分析H.pylori感染情况、病理诊断与组织分型结果，明确慢性胃炎患者H.pylori感染与病理炎症程度...
Synthesis and anti-Helicobacter pylori activity of (4-nitro-1-imidazolylmethyl)-1,2,4-triazoles, 1,3,4-thiadiazoles, and 1,3,4-oxadiazoles
4-Nitroimidazole 1,2,4-triazoles 1,3,4-thiadiazoles 1,3,4-oxadiazoles anti-H. pylori activity
2011/4/6
A series of [(4-nitro-1H-imidazol-1-yl)methyl]-1,2,4- triazoles and 1,3,4-thiadiazoles were prepared and evaluated for their activity against sensitive and resistant H. pylori strains. Study of the st...
Synthesis and in vitro anti-Helicobacter pylori activity of 2-(substituted benzylthio)-5-(5-nitro-2- furyl)-1, 3, 4-thiadiazole derivatives
1,3,4-Thiadiazole nitrofuran anti-Helicobacter pylori activity
2010/4/8
Starting from (5-nitrofuran-2-yl)methylene diacetate, a new series of 2-[(substituted benzyl)thio]-5-(5-nitro-2-furyl)-1,3,4-thiadiazoles (6a-n) were synthesized and the structures of the compounds we...
山东临朐人群HLA等位基因多态性与幽门螺杆菌感染关系的研究Studies of the Relationship of HLA Polymorphisms and the Infection of H.pylori in the Population of Linqu in Shandong Province
人类白细胞抗原（HLA） PCR SSP 幽门螺杆菌 遗传易感性
2008/1/10
摘要为了研究山东临朐地区健康人白细胞抗原（HLA）Ⅰ类等位基因多态性与幽门螺杆菌（Hp）感染的关系，运用序列特异性引物聚合酶链反应（PCRSSP）的方法，检测Hp阳性人群（90例）和Hp阴性人群（49例）的HLAⅠ类和Ⅱ类等位基因。结果在HLAⅠ类（A、B、CW）的共68个等位基因多态中，发现在感染及非感染人群中存在4个显著性差异的位点；在HLAⅡ类（DRB1、DQB1和DRB3、DRB4...
Antagonism against Helicobacter Pylori and Proteolysis of Lactobacillus Helveticus CU631 and Strain Identification
Antagonistic Activity Lactobacilli Helicobacter Pyroli Urease Vacuolatijg Toxicity 16S-23S R RNA Spacer Gene Sequencing
2016/4/11
The antagonistic activities of 30 strains of lactobacilli against Helicobacter pylori were determined and Lactobacillus helveticus CU631 has been selected as the strain which possesses the strongest i...