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GlycA, a novel proinflammatory glycoprotein biomarker, and high-sensitivity C-reactive protein are inversely associated with sodium intake after controlling for adiposity: the Prevention of Renal and Vascular End-Stage Disease study
C-reactive protein diet GlycA glycoproteins inflammation nuclear magnetic resonance spectroscopy sodium excretion
2018/12/3
Background: The extent to which dietary sodium intake may confer alterations in the inflammatory status is unclear. GlycA is a novel proton nuclear magnetic resonance spectroscopy-measured biomarker o...
GlycA, a novel proinflammatory glycoprotein biomarker, and high-sensitivity C-reactive protein are inversely associated with sodium intake after controlling for adiposity: the Prevention of Renal and Vascular End-Stage Disease study
C-reactive protein diet GlycA glycoproteins inflammation nuclear magnetic resonance spectroscopy sodium excretion
2018/12/13
Background: The extent to which dietary sodium intake may confer alterations in the inflammatory status is unclear. GlycA is a novel proton nuclear magnetic resonance spectroscopy-measured biomarker o...
The morphology of porcine oocytes is associated with zona pellucida glycoprotein 3 and integrin beta 2 protein levels--
pig oocyte morphology
2015/4/8
The morphology and quality of oocytes is set during oo- and folliculo-genesis, and is completed during final maturation. Early embryonic development is associated with the morphology of the cumulus-oo...
P-glycoprotein的新功能在肿瘤研究中的进展
P-glycoprotein 多药耐药 增殖 凋亡 迁移 上皮间质转化 血管生成
2015/7/20
肿瘤多药耐药性(multiple drug resistance,MDR)的发生往往伴随着多药耐药基因如MDR1、MRP 1 和BCRP等高表达,其中MDR1 基因编码的P-糖蛋白(P-glycoprotein ,P-gp)是目前公认可以诱发癌细胞发生MDR的重要分子。传统研究认为P-gp主要是作为一个药物泵将化疗药物从细胞内排出从而导致MDR。然而系列研究发现,除了介导MDR以外,P-gp还能够...
Investigations of glycoprotein co-translational maturation in the cell
New protein Protein Endoplasmic reticulum cavity Protein folding Coupling molecules Fold the sensor Membrane glycoprotein
2014/12/11
The earliest steps of nascent protein folding are critical to the overall folding efficiency. Folding events start as soon as the protein is translocated into the endoplasmic reticulum lumen, where th...
The role of the ER glucosyltransferase in the quality control of glycoprotein maturation
Pure sciences Biological sciences Endoplasmic reticulum Glycoprotein Glycoprotein glucosyltransferase 1 Protein folding Protein maturation Glucosyltransferase
2014/12/11
N-linked glycans serve as quality control tags in the eukaryotic secretory pathway. The endoplasmic reticulum (ER) protein UDP-glucose: glycoprotein glucosyltransferase 1 (GT1) is the main enzyme that...
Comparison of α1-Antitrypsin, α1-Acid Glycoprotein, Fibrinogen and NOx as Indicator of Subclinical Mastitis in Riverine Buffalo (Bubalus bubalis)
Acute Phase Proteins Nitric Oxide Subclinical Mastitis and Buffalo
2016/5/11
Mastitis set apart as clinical and sub clinical is a disease complex of dairy cattle, with sub clinical being the most important economically. Of late, laboratories showed interest in developing bioch...
Clinical Significance of P-Glycoprotein Immunohistochemistry and Histomorphologic Factors in Patients with Osteosarcoma
Osteosarcoma Prognosis Immunohistochemistry P-glycoprotein
2015/9/18
Background: Osteosarcoma is the most frequent highly malignant bone tumor with a peak incidence in the second decade of life. Although survival rate increased up to 60-70% within the last 10 years, th...
Clinical Significance of P-Glycoprotein Immunohistochemistry and Histomorphologic Factors in Patients with Osteosarcoma
Osteosarcoma Prognosis Immunohistochemistry P-glycoprotein
2015/9/18
Background: Osteosarcoma is the most frequent highly malignant bone tumor with a peak incidence in the second decade of life. Although survival rate increased up to 60-70% within the last 10 years, th...
Glycoprotein IIb/IIIa Inhibitors in Acute Coronary Syndromes: A new Paradigm in Cardiology
Coronary Syndromes Cardiology Glycoprotein
2009/7/2
Acute coronary syndromes, namely, unstable angina and myocardial infarction, remain a major cause of morbidity and mortality (1). The light has been shed on the pathogenesis of these syndromes by rece...
The Effects of Benzo(A) Pyrene Doxorubicin and Paclitaxel on P170 Glycoprotein
benzo(a)pyrene doxorubicin paclitaxel p170 glycoprotein rat
2009/6/29
B(a)P is a mutagenic, carcinogenic and teratogenic substance. Paclitaxel and doxorubicin are antineoplastic drugs widely used in cancer treatment. The purpose of this study is to observe the effects o...
Determination of Polydispersity of a Human Colonic Mucus Glycoprotein Using Rate-Zonal Centrifugation and Laser Light-Scattering
Polydispersity colonic mucins rate-zonal centrifugation light-scattering
2009/6/25
The colonic epithelium is coated by a visco-elastic gel, mucus that lubricates and protects the mucosa from the external environment. Mucus glycoproteins (mucins, MUCs) are major macromolecular compon...
Increased Prevalence of Glycoprotein IIb/IIIa Leu 33 Pro Polymorphism in End Stage Renal Disease Patients on Hemodialysis
hemodialysis fibrinogen receptor polymorphism glycoprotein platelets CVD
2009/4/14
Traditional atherosclerosis risk factors cannot elucidate the increased prevalence of cardiovascular events in end stage renal disease (ESRD) patients on hemodialysis. A previous study has indicated a...
Effect of zinc on hepatoprotectivity of α1-acid glycoprotein
αl-acid glycoprotein zinc hepatoprotection thermal property
2009/4/1
αl-Acid glycoprotein (AGP) prevented primary hepatocytes from undergoing cell death induced by the chemical toxin, bromobenzene at range from 0.1 to 0.2 mg/ml. Addition of zinc (0.2 mM) to medium cont...
Protein and Glycoprotein Patterns Related to Morphogenesis in Mammillaria gracillis Pfeiff. Tissue Culture
Cactacaeae crown-gall tumour glycoproteins morphogenesis
2009/3/20
As plants with Crassulacean Acid Metabolism (CAM), cacti are highly affected by artificial environmental conditions in tissue culture. Plants of Mammillaria gracillis Pfeiff. (Cactaceae) propagated in...