搜索结果: 1-13 共查到“知识库 genome-wide association studies”相关记录13条 . 查询时间(0.468 秒)
Optimized Homomorphic Encryption Solution for Secure Genome-Wide Association Studies
implementation public-key cryptography RNS variant of approximate homomorphic encryption genome-wide associate studies
2019/2/28
Genome-Wide Association Studies (GWAS) refer to observational studies of a genome-wide set of genetic variants across many individuals to see if any genetic variants are associated with a certain trai...
Identification of loci affecting teat number by genome-wide association studies on three pig populations
Genome-wide Association Study Imputation Meta-analysis Pig Teat Number
2017/3/7
Identification of loci affecting teat number by genome-wide association studies on three pig populations.
Stories and Challenges of Genome Wide Association Studies in Livestock — A Review
QTL Livestock Genome-wide Association
2016/5/18
Undoubtedly livestock is one of the major contributors to the economy of any country. The economic value of livestock includes meat, dairy products, fiber, fertilizer etc. Understanding and identifyin...
Genome Wide Association Studies Using Multiple-lactation Breeding Value in Holsteins
Single Nucleotide Polymorphism Milk Production Traits Lactation, Holstein
2016/5/18
A genome wide association study was conducted using estimated breeding value (EBV) for milk production traits from 1st to 4th lactation. Significant single nucleotide polymorphism (SNP) markers were s...
Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium
arachidonic acid genome-wide association meta-analysis phospholipid trans fatty acids
2018/12/20
Background: Circulating trans fatty acids (TFAs), which cannot be synthesized by humans, are linked to adverse health outcomes. Although TFAs are obtained from diet, little is known about subsequent i...
Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium
arachidonic acid genome-wide association meta-analysis phospholipid trans fatty acids
2018/12/20
Background: Circulating trans fatty acids (TFAs), which cannot be synthesized by humans, are linked to adverse health outcomes. Although TFAs are obtained from diet, little is known about subsequent i...
Efficient Algorithms for Multivariate Linear Mixed Models in Genome-wide Association Studies
Efficient Algorithms Multivariate Linear Mixed Models Genome-wide Association Studies
2013/6/17
Multivariate linear mixed models (mvLMMs) have been widely used in many areas of genetics, and have attracted considerable recent interest in genome-wide association studies (GWASs). However, existing...
Replicability analysis for Genome-wide Association studies
Replicability analysis Genome-wide Association studies
2012/11/22
The paramount importance of replicating associations is well recognized in the genome-wide associaton (GWA) research community, yet methods for assessing replicability of associations are scarce. Publ...
Integrated analysis of variants and pathways in genome-wide association studies using polygenic models of disease
Integrated analysis of variants pathways genome-wide association studies polygenic models of disease
2012/9/18
Many common diseases are highly polygenic, modulated by a large number genetic factors with small effects on suscep-tibility to disease. These small effects are difficult to map reliably in genetic as...
A Bayesian Method for Detecting and Characterizing Allelic Heterogeneity and Boosting Signals in Genome-Wide Association Studies
Bayesian Method Detecting Characterizing Allelic Heterogeneity Boosting Signals Genome-Wide Association Studies
2010/11/16
The standard paradigm for the analysis of genome-wide association studies involves carrying out association tests at both typed and imputed SNPs. These methods will not be optimal for detecting the si...
Methodological Issues in Multistage Genome-Wide Association Studies
Methodological Issues Multistage Genome-Wide Association Studies
2010/11/16
Because of the high cost of commercial genotyping chip technologies, many investigations have used a two-stage design for genome-wide association studies, using part of the sample for an initial disco...
A model selection approach to genome wide association studies
Genome wide association Multiple testing Linear regression,
2010/10/14
For the vast majority of genome wide association studies (GWAS) published so far, statistical analysis was performed by testing markers individually. In this article we present some elementary statis...
Improving power in genome-wide association studies：weights tip the scale
Bonferroni correction Genome-wide association analysis Multiple testing Weightedp-values
2010/4/26
Genome-wide association analysis has generated much discussion about how to preserve power
1 to detect signals despite the detrimental effect of multiple testing on power. We develop a weighted multi...