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构建了棉花抗黄萎病性状的关联群体和遗传分离群体,联合利用全基因组关联分析(GWAS)、QTL- Seq和转录组测序开展了棉花抗黄萎病基因发掘与KASP标记开发研究,获得了5个主效抗黄萎病QTL的候选基因区间,开发出10个可以用于陆地棉抗病性标记辅助选择育种的KASP标记,同时鉴定出8个抗黄萎病候选基因,这些基因主要参与植物基础免疫反应及广谱抗病性,推测基础免疫反应相关基因在抗、感品种间的gDNA&...
The planting of Pinus elliottii Engelm. has now reached close to three million ha in China. Molecular breeding as part of the improvement program for P. elliottii in southern China has been carried ou...
Branching in woody plants affects their ecological benefits and impacts wood formation. To obtain genome-wide insights into the transcriptome changes and regulatory mechanisms associated with branchin...
Polymorphism detection in woody plant species is important in phylogenetics and an essential stage in plant breeding programs. Genotyping has benefitted from the development of next-generation sequenc...
Perceiving the temporal order of sensory events typically depends on participants' attentional state, thus likely on the endogenous fluctuations of brain activity. Using magnetoencephalography, we sou...
Understanding the genetic factors underlying neurodevelopmental and neuropsychiatric disorders is a major challenge given their prevalence and potential severity for quality of life. While large-scal...
A significant proportion of children have unexplained problems acquiring proficient linguistic skills despite adequate intelligence and opportunity. Developmental language disorders are highly heritab...
通过挖掘控制重要农艺性状的基因以提高农作物产量是育种学家一直关注的问题。然而由于农作物遗传背景复杂且基因组庞大, 该过程往往步骤繁琐, 耗时长且成本较高。Mapping-by-sequencing (利用高通量测序进行基因定位, MBS)利用二代测序技术和遗传分离群体混池建库分析的方法成功解决了上述问题, 加快了农作物重要农艺性状的基因定位同时也降低了研究成本。该方法已经成功应用于重要农艺性状相关...
Intron sequences from the elongation factor-1a (EF1a) gene from the marine shrimp Penaeus vannamei reveal extensive variation even among inbred populations of hatchery-raised shrimp. Among 44 indivi...
We present a powerful, general method for producing a pure preparation of single-stranded DNA (ssDNA) sequencing template from doublestranded DNA (dsDNA) amplified using the polymerase chain reaction ...
MicroRNAs (miRNAs) are short non-coding RNAs that post-transcriptionally regulate expression of mRNAs in many biological pathways. Liver plays an important role in the feed efficiency of animals and h...
High-throughput sequencing technologies are currently revolutionizing the field of biology and medicine, yet bioinformatic challenges in analysing very large data sets have slowed the adoption o...
Species invasions cause significant ecological and economic damage, and genetic information is important to understanding and managing invasive species. In the ocean, many invasive species have...

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