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Comparison of Metformin and Simvastatin Administration in Women With Polycystic Ovary Syndrome Before Intra-Cytoplasmic Sperm Injection Cycle: A Prospective, Randomized, Clinical Trial Study
Metformin Simvastatin Polycystic Ovary Syndrome Intracytoplasmic Sperm Injection
2015/12/29
Background: Drugs administration as a pretreatment regiment before ICSI cycle in PCOs patients could enhance the success rate.
Recently, we conducted a preclinical investigation to find the ameliorative properties of metformin on renal biochemical and histologic alterations of gentamicin-induced kidney damage in male Wistar r...
Use of metformin during pregnancy for women with polycystic ovary syndrome
Metformin Polycystic Ovary Syndrome Pregnancy Complications
2013/1/31
Objective: The purpose of this article is to review the literature assessing foetal and maternal pregnancy outcomes in women with PCOS who used metformin during pregnancy. Study Design: A literature s...
Quantitative Spot-Test Analysis of Metformin in Pharmaceutical Preparations Using Ultraviolet-Visible Diffuse Reflectance Spectroscopy
Quantitative Spot-Test Analysis Metformin Pharmaceutical Ultraviolet-Visible Diffuse Reflectance Spectroscopy
2010/9/17
A quantitative spot-test for the determination of metformin in pharmaceutical preparations using diffuse UV-visible reflectance is reported. The procedure is quite simple, involving in the formation o...
COMPARISON OF SERUM HOMOCYSTEINE LEVEL IN METFORMIN VERSUS GLIBENCLAMIDE TREATED TYPE 2 DM PATIENTS
COMPARISON SERUM HOMOCYSTEINE LEVEL METFORMIN VERSUS GLIBENCLAMIDE
2009/12/31
Background: Diabetes mellitus is the most common cause of renal failure, blindness, non- traumatic amputation and neuropathy. Homocysteine, a sulfurated amino acid, has a close correlation with Methio...
A Rare Side Effect of Metformin: Metformin-Induced Hepatotoxicity
Metformin metformin-associated lactic acidosis hepatotoxicity side effect
2009/6/17
Metformin is an oral hypoglycemic agent that is commonly used in the treatment of type 2 diabetes mellitus. While metformin-associated metabolic acidosis is a widely recognized side effect of this dru...
Effect of Metformin or Gliclazide on Lipid Peroxidation and Antioxidant Levels in Patients with Diabetes Mellitus
Diabetes mellitus gliclazide metformin antioxidant enzymes malondialdehyde
2009/6/16
Aim: The association between oxidative stress and diabetic complications is well known. The main goal of antidiabetic therapy is to prevent the complications of diabetes. Gliclazide (sulfonylurea) and...
Metformin Restores the Penile Expression of Nitric Oxide Synthase in High-Fat–Fed Obese Rats
AMP-activated protein kinase penile tissue
2008/12/24
Obesity is a well-known risk factor for erectile dysfunction, which is associated with reduced penile nitric oxide synthase (NOS) expression. Recently it was reported that metformin activates AMP...
Comparison of a generic and a brand metformin products in type II diabetes:A double blind randomized clinical trial study
Type 2 diabetes mellitus Metformin Clinical trial Therapeutic effects
2010/4/8
Metformin is often prescribed for glycemic control in type II diabetes mellitus. This drug is the first line treatment for obese without renal or liver failure. Different pharmaceutical types of Metfo...
Invitro evaluation and optimization of controlled release floating drug delivery system of metformin hydrochloride
Invitro evaluation and optimization controlled release floating drug delivery system metformin hydrochloride
2010/2/8
The floating microspheres have been utilized to obtain prolonged and uniform release in the stomach for development of a once daily formulation. The major advantage of the preparation technique includ...