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Engineers devise a way to selectively turn on RNA therapies in human cells（图）
人类细胞 RNA疗法 治疗性蛋白质 癌症治疗
2023/6/21
Researchers at MIT and Harvard University have designed a way to selectively turn on gene therapies in target cells, including human cells. Their technology can detect specific messenger RNA sequences...
Different cell types—say, heart, liver, blood, and sperm cells—possess characteristics that help them carry out their unique jobs in the body. In general, those characteristics are hard-wired. Without...
A typical bacterial genome contains more than 4,000 genes, which encode all of the proteins that the cells need to survive. How do cells know just how much of each protein they need for their everyday...
New CRISPR-based tool inserts large DNA sequences at desired sites in cells（图）
CRISPR 新型工具 大DNA序列 PAST 基因工程
2023/6/21
Building on the CRISPR gene-editing system, MIT researchers have designed a new tool that can snip out faulty genes and replace them with new ones, in a safer and more efficient way.
In a single day, enough sunlight strikes Earth to power the world for an entire year—that is, if we can find a way to capture that energy cheaply and efficiently. While the cost of solar energy has de...
Cancer cells selectively load ‘drones’ to keep T cells from infiltrating tumors（图）
癌细胞 选择性加载 T细胞 浸润肿瘤
2023/7/7
Checkpoint inhibitor drugs have been a gamechanger for many cancer patients. Yet around 70% don’t respond to these medications, which work by removing the “brakes” on the immune system’s response to a...
Within a given tissue or organ, cells may appear very similar or even identical. But at the molecular level, these cells can have small differences that lead to wide variations in their functions.
Perovskites hold promise for creating solar panels that could be easily deposited onto most surfaces, including flexible and textured ones. These materials would also be lightweight, cheap to produce,...
Cells in complex organisms undergo frequent changes, and researchers have struggled to monitor these changes and create a comprehensive profile for living cells and tissues. Historically researchers h...
MIT researchers have discovered that before cells start to divide, they do a little cleanup, tossing out molecules that they appear not to need anymore.
Reducing the use of fossil fuels will have unintended consequences for the power-generation industry and beyond. For example, many industrial chemical processes use fossil-fuel byproducts as precursor...
Acommon building material, asbestos is the term used to describe a range of naturally growing minerals. Serious diseases, including mesothelioma and lung cancer, can arise decades after coming into co...
While neurons and glial cells are by far the most numerous cells in the brain, many other types of cells play important roles. Among those are cerebrovascular cells, which form the blood vessels that ...
Cornell chemists have discovered a class of nonprecious metal derivatives that can catalyze fuel cell reactions about as well as platinum, at a fraction of the cost.
