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Huge libraries of drug compounds may hold potential treatments for a variety of diseases, such as cancer or heart disease. Ideally, scientists would like to experimentally test each of these compounds...
With the release of platforms like DALL-E 2 and Midjourney, diffusion generative models have achieved mainstream popularity, owing to their ability to generate a series of absurd, breathtaking, and of...
上海市肿瘤研究所金浩杰研究员和Rene Bernards院士合作在Nature Reviews Drug Discovery杂志发表长篇综述文章：癌症联合靶向治疗的背景、优势与挑战（图）
金浩杰研究员 癌症 肿瘤药物 肿瘤细胞
2023/1/13
近日，上海市肿瘤研究所金浩杰研究员与René Bernards院士作为共同通讯作者在Nature Reviews Drug Discovery期刊上发表了长篇综述文章“Rational combinations of targeted cancer therapies: background, advances and challenges”，对癌症联合靶向治疗策略的背景、优势及面临的挑战进行全面...
Over the past few decades, very few new antibiotics have been developed, largely because current methods for screening potential drugs are prohibitively expensive and time-consuming. One promising new...
In their quest to discover effective new medicines, scientists search for drug-like molecules that can attach to disease-causing proteins and change their functionality. It is crucial that they know t...
NSF provides support for drug discovery platform for hard-to-treat cancers（图）
NSF provides support drug discovery platform hard-to-treat cancers
2020/5/9
A new round of support will help a Purdue University-affiliated startup further develop a platform designed to create drugs for people with hard-to-treat cancers.Akanocure Pharmaceuticals, Inc., ...
AI accelerating drug discovery to fight COVID-19（图）
AI accelerating drug discovery fight COVID-19
2020/5/9
Researchers are running a global race to discover a vaccine, drug or combination of treatments that can disrupt the SARS-CoV-2 virus, which causes the COVID-19 disease, and prevent widespread deaths.M...
Scripps Florida Scientists Develop Drug Discovery Approach to Predict Health Impact of Endocrine-Disrupting Chemicals
Scripps Florida Scientists Drug Discovery Approach Predict Health Endocrine-Disrupting Chemicals
2017/1/9
Breast cancer researchers from the Florida campus of The Scripps Research Institute (TSRI) have developed a novel approach for identifying how chemicals in the environment—called environmental estroge...
Anticancer drug discovery:structures of KDM5 histone demethylase inhibitors
Anticancer drug KDM5 histone demethylase inhibitors
2016/8/1
When doctors hurl toxic death at cancer cells, often a few will survive and come back. A family of enzymes called KDM5 histone demethylases is emerging as important for this resilience, and drugs that...
Researchers engineer 'Cas9' animal models to study disease and inform drug discovery
animal drug disease
2014/10/9
Cambridge, Mass. September 25th, 2014 — Researchers from the Broad Institute and Massachusetts Institute of Technology have created a new mouse model to simplify application of the CRISPR-Cas9 system ...
The discovery that a cancer drug is hiding in sunflower seeds has won a UQ plant scientist a national award.
In the last 10 years, the growth of the Internet has made ranking algorithms one of the hottest topics in computer science. The most famous ranking algorithm is Google’s, which determines the order of...