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Distribution of Type I Collagen Morphologies in Bone: Relation to Estrogen Depletion
AFM Ultrastructure disease diagnosis
2014/11/6
Bone is an amazing material evolved by nature to elegantly balance structural and metabolic needs in the body. Bone health is an integral part of overall health, but our lack of understanding of the u...
Cortical Bone Mechanical Properties Are Altered in an Animal Model of Progressive Chronic Kidney Disease
chronic kidney disease whole bone mechanical properties
2014/11/6
Chronic kidney disease (CKD), which leads tocortical bone loss and increasedporosity,increases therisk of fracture. Animal models have confirmed that these changes compromise whole bone mechanical pro...
Multi-scale Analysis of Bone Chemistry, Morphology and Mechanics in the oim Model of Osteogenesis Imperfecta
Atomic force microscopy Raman Spectroscopy Reference Point Indentation MicroCT Crystallinity Modulus
2014/11/6
Osteogenesis imperfecta is a congenital disease commonly characterized by brittle bones and caused by mutations in the genes encoding Type I collagen, the single most abundant protein produced by the ...
In Vitro Analysis of Biodegradable Polymer Blend/Hydroxyapatite Composites for Bone Tissue Engineering
biodegradable hydroxyapatite poly(caprolactone) PLGA tissue engineering
2009/12/22
Blends of biodegradable polymers, poly(caprolactone)
and poly(D,L-lactic-co-glycolic acid), have been examined
as scaffolds for applications in bone tissue engineering.
Hydroxyapatite granules have...
Characterization of osteoblast-like behavior of cultured bone marrow stromal cells on various polymer surfaces
biomaterials bone substitutes bone marrow osteoblast mineralization polymeric biomaterials
2009/12/22
The creation of novel bone substitutes requires a
detailed understanding of the interaction between cells and
materials. This study was designed to test certain polymers,
specifically poly(caprolac...
Bone formation in β-tricalcium phosphate-filled bone defects of the rat femur:Morphometric analysis and expression of bone related protein mRNA
β-tricalcium phosphate-filled bone rat femur Morphometric analysis bone related protein mRNA
2009/3/2
The purpose of the current study was to evaluate the bone formation when β-tricalcium phosphate (TCP) was implanted in bone defects of rat femurs. β-TCP granules were applied to defects created in t...