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Differential methylation in steroid 5 alpha-reductase isozyme genes in epididymis, testis, and liver of the adult rat
Gene methylation gene expression androgens dihydrotestosterone eukaryotic adenine methylation
2009/2/17
DNA methylation has been largely involved in the regulation of tissue-specific gene expression. The aim of the study was to determine the methylation pattern of steroid 5 alpha-reductase genes 1 and 2...
Structure of the rRNA genes in the hamster sperm nucleus
Nuclear matrix nucleolus DNA structure DNA loop
2009/2/13
We have examined the structure of the major ribosomal RNA (rRNA) genes in the hamster sperm nucleus, using fluorescent in situ hybridization (FISH). The rRNA genes are present as tandemly repeated...
Mouse Spam1（PH-20）：evidence for its expression in the epididymis and for a new category of spermatogenic-expressed genes
Mouse Spam epididymis spermatogenic-expressed genes
2008/12/25
The gene for the sperm adhesion molecule 1 (PH-20), SPAM1, has been known to be testis-specific and exclusively haploid expressed. We show that in mice, the 2 common isoforms of the protein (Spam1...
Changes in the expression of junctional and nonjunctional complex component genes when inter-sertoli tight junctions are formed in vitro
Changes junctional nonjunctional complex component genes inter-sertoli tight junctions
2008/12/25
Throughout spermatogenesis, germ cells move progressively from the basal to the adluminal compartment, which is accompanied by continual disassembly and reassembly of intercellular junctions sugge...
Influence of a Leptin Deficiency on Testicular Morphology, Germ Cell Apoptosis, and Expression Levels of Apoptosis-Related Genes in the Mouse
Spermatogenesis seminiferous tubules testis cytomorphometry micro array
2008/12/24
Leptin-deficient (ob/ob) male mice are morbidly obese and exhibit impaired reproductive function. The objective of this study was to assess the effect of a leptin deficiency on testicular morphology...
Identification of Polymorphisms in the Hrb, GOPC, and Csnk2a2 Genes in Two Men With Globozoospermia
Identification Polymorphisms Hrb, GOPC, Csnk2a2 Genes Men Globozoospermia
2008/12/23
Globozoospermia, or round-headed sperm syndrome, is a unique form of male infertility characterized by sperm possessing a round head, lack of an acrosome, and a disorganized midpiece and tail. It ...
Single-Nucleotide Polymorphisms and Mutation Analyses of the TNP1 and TNP2 Genes of Fertile and Infertile Human Male Populations
Protamine transition nuclear protein sperm male infertility genome promoter SNPs
2008/12/23
Previously, we examined the relationship between protamine gene variations and human male infertility. In this study, we show specific variability in the transition nuclear protein genes (TNPs) of...
Estrogenic Regulation of Signaling Pathways and Homeobox Genes During Rat Prostate Development
Estrogenic Regulation Signaling Pathways Homeobox Genes Rat Prostate Development
2008/12/22
The developing prostate gland is regulated by its hormonal milieu, most notably androgens, which dictate its growth and differentiation (Price, 1936; Lasnitzki and Mizuno, 1980). In addition, the ...
Sonic Hedgehog Pathway Genes Are Expressed and Transcribed in the Adult Mouse Epididymis
Gene transcription efferent duct ligation
2008/12/22
One role of the hedgehog (hh) signaling pathway during development is to assist in establishing pattern orientation in the embryo. The structure and function in the adult epididymis is highly patter...
Identification of Differentially Expressed Genes in Mouse Spermatogenesis
Type A spermatogonia pachytene spermatocytes round spermatids spermatogenesis
2008/12/19
Complementary DNA microarray and quantitative polymerase chain reaction were used as tools for discovering genes that are differentially expressed in the mouse under normal physiological condition...
Normal sperm production (spermatogenesis), maturation (spermiogenesis), delivery to and passage through the female genital tract (ejaculation and sperm transport), and function (capacitation, egg pene...
Expression of Testicular Germ Cell Genes Identified by Differential Display Analysis
Testicular Germ Cell Genes Differential Display Analysis
2008/12/19
Using differential display reverse transcriptase–polymerase chain reaction (DDRT-PCR) we identified transcripts encoding for the RNA helicase mDEAH9, Ran binding protein 5 (RanBP5), and 3 novel comp...