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Bisphosphonates suppress periosteal osteoblast activity independently of resorption in rat femur and tibia
rodent modeling and remodeling osteoblast
2014/12/4
Recent studies demonstrate that bisphosphonates suppress bone resorption by leading to apoptosis of the osteoclast and inhibiting the differentiation to mature osteoclasts. The influence of bisphospho...
Resolution of Inflammation Induces Osteoblast Function and Regulates the Wnt Signaling Pathway
inflammation osteoblast
2014/12/4
Objective Inflammation in the bone microenvironment stimulates osteoclast differentiation, resulting in uncoupling of resorption and formation. Mechanisms contributing to the inhibition of osteoblast ...