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PREDICTING NUCLEAR GENE COALESCENCE FROM MITOCHONDRIAL DATA: THE THREE-TIMES RULE
molecular systematics monophyly whales
2015/12/17
Coalescence theory predicts when genetic drift at nuclear loci will result in fixation of sequence differences
to produce monophyletic gene trees. However, the theory is difficult to appl...
Molecular Evolution of a Portion of the Mitochondrial 16S Ribosomal Gene Region in Scleractinian Corals
Gene Region Scleractinian Corals
2015/12/17
Relationships among families and suborders
of scleractinian corals are poorly understood because of
difficulties 1) in making inferences about the evolution
of the morphological characters used in ...
Characterization of the Mitochondrial Proteome in Pyruvate Dehydrogenase Kinase 4 Wild-Type and Knockout Mice
Starvation Mitochondria Proteomics PDK4
2015/5/25
The goal of this study was to determine the effect of a PDK4 (pyruvate dehydrogenase kinase isoenzyme 4) knock-out on mitochondrial protein expression. A 2-D gel based mass spectrometry approach was u...
Identification and characterization of altered mitochondrial protein acetylation in Friedreich's ataxia cardiomyopathy
Identification and characterization mitochondrial protein acetylation
2015/5/21
Friedreich’s Ataxia (FRDA) is a rare and poorly understood autosomal recessive disease caused by a pathological deficiency of the mitochondrial protein frataxin. Patients suffer neurodegeneration, ata...
A Phylogenetic Analysis of Armored Scale Insects, Based Upon Nuclear, Mitochondrial, and Endosymbiont Gene Sequences
Diaspididae Coccoidea evolution
2015/1/4
Armored scale insects (Hemiptera: Diaspididae) are among the most invasive insects in the world. They have unusual genetic systems, including diverse types of paternal genome elimination (PGE) and par...
线粒体DNA修复系统相关酶的研究进展 Progress of Enzyme in Mitochondrial DNA Repair System
线粒体DNA DNA修复 酶 研究进展
2008/1/10
摘要线粒体DNA（mtDNA）编码线粒体电子传递系统的亚单位以及构建翻译机器所需的各种rRAN和tRNA。mtDNA编码的每一个亚单位都是线粒体完成正常的氧化磷酸化过程所必需的，因此，线粒体DNA的完整性对于生物体的生存十分重要。长期以来，人们一直认为线粒体中不存在DNA的修复。近年来在线粒体提取物中却检测到了一定数量的修复因子，提示线粒体中存在DNA的修复。主要对线粒体修复系统中相关酶的研究进展...
肝癌组织中线粒体DNA D-Loop区碱基变异与ROS水平Mutations in the D-Loop Region of Mitochondrial DNA and the ROS Level in the Tissue of Hepatocellular Carcinoma
线粒体DNA D-Loop 原发性肝癌 突变 活性氧类物质
2008/1/6
摘要
为了探讨ROS水平与突变的关系，对原发性肝癌线粒体DNA区的突变情况进行研究，同时对原发性肝癌患者组织细胞内ROS进行测定。选择20例原发性肝癌组织及其邻近的癌旁组织，用PCR方法将线粒体DNA D-Loop扩增后测序。组织内ROS的水平采用流式细胞技术测定。结果表明在20对原发性肝癌组织中存在8对mtDNA突变，突变率为40%,共发现突变位点53个，包括2个插入，11个缺失...
云南保山猪线粒体DNA D-loop区序列初步分析Primary Analysis of Mitochondrial DNA D-loop Region Sequence in Baoshan Pig
保山猪 线粒体DNA D-loop 高变区I 遗传多样性
2007/12/31
摘要
摘要：为了解云南保山猪(Baoshan pig)的遗传多样性及其遗传背景，我们测定了19个个体线粒体DNA D-loop高变区I 15 363～15 801片段序列438 bp。检测到10种单倍型，包括8个多态位点，其中5次T/C转换、1次G/A转换、1次G/C颠换和1次A/T颠换，其A、T、G、C碱基的平均含量分别为35.4%、26.9%、13.2%和24.5%，A+T含量(62.3%)...
人线粒体tRNALeu(UUR)基因A3243G点突变对其亮氨酰化活性的影响Effects of A3243G Point Mutation on Aminoacylation of Human Mitochondrial tRNALeu(UUR)
人线粒体tRNALeu(UUR) A3243G点突变 氨酰化 体外转录 人线粒体亮氨酰tRNA结合酶
2007/12/30
摘要化学法合成人线粒体野生型与A3243G点突变型tRNALeu(UUR)基因,体外转录生成相应的tRNALeu(UUR),表达并纯化人线粒体亮氨酰tRNA合成酶(mtLeuRS),用mtLeuRS催化野生型与突变型tRNALeu(UUR)与亮氨酸结合，分别检测两种类型tRNALeu(UUR)的氨酰化动力学常数。结果表明，野生型tRNALeu(UUR)的Km/Kcat仅为突变型tRNALeu(UU...
期刊信息
篇名
Mitochondrial DNA sequence evolution and conservation relevance of Snub-nosed Langurs
语种
英文
撰写或编译
作者
Zhang Y P,Ryder O A
第一作者单位
刊物名称
Chinese Jouranl of Genetics
页面
1997,24(1):P.7-14
出版日期
1997年...
期刊信息
篇名
Presence of plastid and absence of mitochondrial DNA in male reproductive cells as evidence for cytoplasmic inheritance in Turnera ulmifolia and Zantedeschia aethiopica
语种
英文
撰写或编译
作者
吉栩,张泉,刘旸...
期刊信息
篇名
A Preliminary Study on the Variability of the mitochondrial DNA control region in populations of finless porpoises, Neophocaena phocaenoides, in Chinese Waters. (In: Biology and Conservation o...