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Lesions in the Central Nucleus of the Amygdala:Discriminative Avoidance Learning,Discriminative Approach Learning,and Cingulothalamic Training-Induced Neuronal Activity
amygdala cingulate cortex limbic thalamus avoidance learning approach learning discrimination
2015/8/7
The amygdala is critically involved in discriminative avoidance learning. Large lesions of the amygdala block discriminative avoidance learning and abolish cingulothalamic training-induced neuronal ac...
Limbic Thalamic Lesions,Appetitively Motivated Discrimination Learning,and Training-Induced Neuronal Activity in Rabbits
cingulate cortex discrimination approach limbic thalamus learning attention neuronal activity
2015/8/7
A substantial literature implicates the anterior and mediodorsal (limbic) thalamic nuclei and the reciprocally interconnected areas of cingulate cortex in learning, memory, and attentional processes. ...
妊娠合并糖尿病诱发胚胎先天性神经管缺陷动物模型的MAP 激酶信号传导机制MAP Kinase Signal Pathway in Hyperglycemia-induced Congenital Neural tube defects
神经管缺陷 糖尿病 激酶 ERK JNK/SAPK RAF-1 动物模型
2008/1/20
摘要
为了揭示妊娠合并糖尿病诱发胚胎先天性神经管缺陷的分子机制,并探讨其有效的防治方法。 实验选用6个实验组的 Sprague-Dawley 大鼠:第1组为常规饲养的正常对照组;第2组尾静脉注射65mg/kg Streptozotocin (STZ) 构建妊娠合并糖尿病、且诱发先天性神经管缺陷的实验组大鼠;第3组为STZ构建的糖尿病、但胚胎不伴有先天性神经管缺陷的大鼠模型;第4、5、6 组为 S...