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Higgs Discovery and the Look Elsewhere Effect
Higgs particle discovery condition Bayesianism 5 sigma limit collider physics
2016/6/12
The discovery of the Higgs particle required a signal of five sigma significance. The rigid application of that condition is a convention that disregards more specific aspects of the given experiment....
Scientific Reasoning Is Material Inference: Combining Confirmation, Discovery, and Explanation
inference concepts confirmation induction
2009/9/11
Whereas an inference (deductive as well as inductive) is usually viewed as being valid in virtue of its argument form, the present paper argues that scientific reasoning is material inference, i.e., j...
How Values in Scientific Discovery and Pursuit Alter Theory Appraisal
scientific discovery pursuit non-epistemic values hormesis endocrine disruption
2009/6/24
Philosophers of science readily acknowledge that non-epistemic values influence the discovery and pursuit of scientific theories, but many tend to regard these influences as epistemically uninterestin...
Multi-level complexities in technological development: Competing strategies for drug discovery
applied science pharmaceuticals development methodology technology
2009/4/29
Drug development regularly has to deal with complex circumstances on two levels: the local level of pharmacological intervention on specific target proteins, and the systems level of the effects of ph...