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Any serious study of the uses of molecular models in chemistry has to mention play as an essential component. A research chemist will use them not unlike a young child playing with a toy: exploring th...
Beyond dematerialization and inscription Does the materiality of molecular models really matter?
molecular models materiality representation stereochemistry
2008/4/7
Taking a critical stance towards the notions of dematerialization and inscription, this paper considers the role of physical molecular models in chemical research, specifically in the development of s...
Pragmatism, Belief, and Reduction Stereoformulas and Atomic Models in Early Stereochemistry
atomic models in 19th century chemistry stereochemistry
2008/4/7
In this paper I explore the character and role of stereoformulas and models of the atom that appeared in the early history of stereochemistry, including those of Jacobus Henricus van’t Hoff, Aemilius ...
The Epistemological Status of Theoretical Models of Molecular Structure
rigid and dynamic model of molecular structure representation quantum theory of molecular structure
2008/4/7
For many decades, chemists regarded rigid models of molecular structure as representing structures of real molecules as their attributes. However, new experimental data required a new theoretical conc...
Models and analogies in science
models analogies idealization truth molecular spring-and-ball models
2008/4/7
Science makes extensive use of models, i.e. simplified or idealized representations of the systems found in the physical world. Models fall into at least two categories: mathematical and physical mode...
Neural network models of protein domain evolution
models in biochemistry protein domain evolution neural networks ethics of modeling
2008/4/7
Protein domains are complex adaptive systems, and here a novel procedure is presented that models the evolution of new functional sites within stable domain folds using neural networks. Neural network...
Biogeochemical Models in the Environmental Sciences The Dynamical System Paradigm and the Role of Simulation Modeling
models in biogeochemistry dynamical system simulation model self-modifying system complexity
2008/4/7
Dynamical systems are the paradigm for the representation of complex systems. The fixed encoding in a closed set of equations, however, contrasts with the openness of biogeochemical systems. Parameter...
Laws and Models in a Theory of Idealization
approximation laws of nature idealized laws ceteris paribus laws
2008/4/1
In this paper, I first give a brief summary of a critique of the traditional theories of approximation and idealization; and after identifying one of the major roles of idealization as detaching compo...
Animal Models of Depression in Neuropsychopharmacology qua Feyerabendian Philosophy of Science
Animal Models Depression Mental Illness Feyerabend
2008/4/1
The neuropsychopharmacological methods and theories used to investigate the nature of depression have been viewed as suspect for a variety of philosophical and scientific reasons. Much of this critici...
Bayesian models and simulations in cognitive science
Bayesian models neuroscience models cognitive science
2008/4/1
Bayesian models can be related to cognitive processes in a variety of ways
that can be usefully understood in terms of Marr's distinction among three levels of explanation: computational, algorithmic...
Physical Pictures: Engineering Models circa 1914 and in Wittgenstein's Tractatus
model Wittgenstein dimensional analysis Buckingham
2008/3/31
In 1914, Wittgenstein recorded an incident in his Notebooks that he later mentioned to several friends as occasioning a major insight for his views in the Tractatus that propositions represent by bein...
Mathematical Models in Newton’s Principia: A New View of the “Newtonian Style”
Isaac Newton Principia (hypothetical-deductive) methodology
2008/3/31
In this essay I argue against Bernard I. Cohen’s influential account of Newton’s methodology in the Principia: the “Newtonian Style”. The crux of Cohen’s account is the successive adaptation of “menta...
Bayesian models and simulations in cognitive science
Bayesian models neuroscience models cognitive science computer vision
2011/9/7
Bayesian models can be related to cognitive processes in a variety of ways that can be usefully understood in terms of Marr's distinction among three levels of explanation: computational, algorithmic ...
Mathematical Models in Newton’s Principia: A New View of the “Newtonian Style”
Isaac Newton Principia (hypothetical-deductive) methodology I. Bernard Cohen Newtonian Style models models as mediators
2011/9/7
In this essay I argue against Bernard I. Cohen’s influential account of Newton’s methodology in the Principia: the “Newtonian Style”. The crux of Cohen’s account is the successive adaptation of “menta...
Animal Models of Depression in Neuropsychopharmacology qua Feyerabendian Philosophy of Science
Animal Models Depression Mental Illness Feyerabend Pluralism Method Theory
2011/9/8
The neuropsychopharmacological methods and theories used to investigate the nature of depression have been viewed as suspect for a variety of philosophical and scientific reasons. Much of this critici...