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Any serious study of the uses of molecular models in chemistry has to mention play as an essential component. A research chemist will use them not unlike a young child playing with a toy: exploring th...
Taking a critical stance towards the notions of dematerialization and inscription, this paper considers the role of physical molecular models in chemical research, specifically in the development of s...
In this paper I explore the character and role of stereoformulas and models of the atom that appeared in the early history of stereochemistry, including those of Jacobus Henricus van’t Hoff, Aemilius ...
For many decades, chemists regarded rigid models of molecular structure as representing structures of real molecules as their attributes. However, new experimental data required a new theoretical conc...
Science makes extensive use of models, i.e. simplified or idealized representations of the systems found in the physical world. Models fall into at least two categories: mathematical and physical mode...
Protein domains are complex adaptive systems, and here a novel procedure is presented that models the evolution of new functional sites within stable domain folds using neural networks. Neural network...
Dynamical systems are the paradigm for the representation of complex systems. The fixed encoding in a closed set of equations, however, contrasts with the openness of biogeochemical systems. Parameter...
In this paper, I first give a brief summary of a critique of the traditional theories of approximation and idealization; and after identifying one of the major roles of idealization as detaching compo...
The neuropsychopharmacological methods and theories used to investigate the nature of depression have been viewed as suspect for a variety of philosophical and scientific reasons. Much of this critici...
Bayesian models can be related to cognitive processes in a variety of ways that can be usefully understood in terms of Marr's distinction among three levels of explanation: computational, algorithmic...
In 1914, Wittgenstein recorded an incident in his Notebooks that he later mentioned to several friends as occasioning a major insight for his views in the Tractatus that propositions represent by bein...
In this essay I argue against Bernard I. Cohen’s influential account of Newton’s methodology in the Principia: the “Newtonian Style”. The crux of Cohen’s account is the successive adaptation of “menta...
Bayesian models can be related to cognitive processes in a variety of ways that can be usefully understood in terms of Marr's distinction among three levels of explanation: computational, algorithmic ...
In this essay I argue against Bernard I. Cohen’s influential account of Newton’s methodology in the Principia: the “Newtonian Style”. The crux of Cohen’s account is the successive adaptation of “menta...
The neuropsychopharmacological methods and theories used to investigate the nature of depression have been viewed as suspect for a variety of philosophical and scientific reasons. Much of this critici...

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