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Exocyst subunit VviExo70B is degraded by ubiquitin ligase VviPUB19 and they regulate drought and salt tolerance in grapevine
Vitis vinifera Exocyst subunit Ubiquitin ligase Drought stress Salt stress ABA
2023/11/16
The exocyst complex comprises secretory vesicle tethering proteins and Exo70 is a subunit of exocyst which is responsible for cell exocytosis and vesicle transport. In Arabidopsis, Exo70B1 and Exo70B2...
Structural Aspects of Plant Hormone Signal Perception and Regulation by Ubiquitin Ligases
phytohormone signaling Ubiquitin Ligases Structural Aspects
2024/2/4
Hormonal cues regulate many aspects of plant growth and development, facilitating the plant's ability to systemically respond to environmental changes. Elucidating the molecular mechanisms governing t...
2016冷泉港学术会议：泛素家族（Cold Spring Harbor conference on The Ubiquitin Family）
Systems Biology Proteasome
2017/1/19
We are pleased to host the ninth Cold Spring Harbor meeting on The Ubiquitin Family, which will will begin at 7:30 pm on Tuesday, April 18 and run through lunch on Saturday, April 22, 2017. The meetin...
The language-related transcription factor FOXP2 is post-translationally modifid with small ubiquitin-like modifirs
language-related transcription factor FOXP2 post-translationally modifid small ubiquitin-like modifirs
2016/5/3
Mutations affecting the transcription factor FOXP2 cause a rare form of severe speech and language disorder. Although it is clear that sufficient FOXP2 expression is crucial for normal brain developme...
The ubiquitin E3 ligase Human Homolog of Drosophila Ariadne-1 (HHARI) is a structural and functional homolog of Parkin and is required for myogenesis
Autosomal genes Parkinson's disease human beings parkinsonism E3 ubiquitin ligase neurons dopaminergic neurons
2014/12/11
Several genes implicated in Parkinson's disease (PD) encode components of the ubiquitin-proteasome pathway. In a specific form of PD (human Autosomal Recessive Juvenile Parkinsonism, AR-JP), loss of f...
Regulation of Notch signaling by the E3 ubiquitin ligase Cbl-b and its role in CD4+ T cell anergy
Cell life cycle T cell signal T cell activation and E3 ubiquitin ligase
2014/12/11
Notch signaling is an evolutionarily conserved pathway that mediates a variety of cell fate decisions. In the immune system, the Notch pathway plays an important role throughout the life of T cells. C...
The Parkin-like ubiquitin E3 ligase Ariadne-1 in the mammalian brain: Potential implications for neurodegenerative disease
Parkinson's disease movement disorders dopaminergic neurons gene encoding protein ubiquitin proteasome system enzyme E3 ubiquitin ligase
2014/12/10
Parkinson’s disease (PD) is a movement disorder characterized by a massive loss of dopaminergic neurons of nigrostriatal origins. Several genes associated with familial cases of PD encode proteins tha...
由上海交通大学医学院和美国德州大学M D Anderson癌症中心联合主办，上海市细胞生物学学会协办的第七届“SUMO、泛素和类泛素蛋白：对人类疾病的影响” 国际会议 （7th International Conference SUMO, Ubiquitin, UBL Proteins: Implications for Human Diseases）于2014年5月10-13日在上海交通大学医学...
Expression Profiling of WSSV ORF 199 and Shrimp Ubiquitin Conjugating Enzyme in WSSV Infected Penaeus monodon
WSSV 199 Shrimp Ubiquitin Conjugating Enzyme Penaeus monodon)
2016/5/10
White spot syndrome virus (WSSV) is one of the major viral pathogens affecting shrimp aquaculture. Four proteins, WSSV199, WSSV 222, WSSV 249 and WSSV 403, from WSSV are predicted to encode a RING-H2 ...
Characterisation of a Polyclonal Antiserum Againts Ubiquitin and its use in the Investigation of Ubiquitin Conjugate Distribution in Normal and Stressed 3T3-LI Cells
Ubiquitin Heat Shock Stress
2009/7/2
Antiserum against ubiquitin was used to identify ubiquitin conjugates in 3T3- LI cells, and to investigate changes in the amount and distribution of these conjugates in cells subjected to stress. Stre...
The Intracellular Concentration of Components of the Ubiquitin System in A549 Culture Cells During UV Treatment
UV Treatment ubiquitin activating enzyme (E1) ubiquitin conjugating enzyme (E2)
2009/6/30
This study attempts to determine a link between the intracellular components of the ubiquitin (Ub) system and the process of DNA repair in eukaryotes. It is possible to investigate this link in two wa...
Expression of the 8 kDa Heat Shock Protein (Ubiquitin) in Psoriasis
Ubiquitin psoriasis immunohistochemistry
2009/6/29
The 8kDa protein (ubiquitin) is a member of the small heat shock protein (hsb) family. Ubiquitin may additionally be involved in the pathogenesis of various diseases. Intracellular accumulation of ubi...
Cell Cycle Regulation through Ubiquitin/Proteasome-Mediated Proteolysis in Plants
CDK cyclin 26S proteasome
2009/6/10
Understanding the mechanism of cell cycle control in plants is important for agricultural technology enabling enhancement of growth rate and then crop yield. Progression of the cell cycle requires the...
Expression of ubiquitin-related enzymes in the suprachiasmatic nucleus with special reference to ubiquitin carboxy-terminal hydrolase UchL1
ubiquitin-related enzymes suprachiasmatic nucleus
2009/3/2
There is growing evidence that ubiquitin-proteasome system plays an important role for the generation of circadian rhythms in mice as in Drosophila. Here we examined the expression of ubiquitin-rela...
Immunoreactive ubiquitin in human seminal plasma
Immunoreactive ubiquitin human seminal plasma
2009/2/12
The polypeptide ubiquitin, up to now almost exclusively discovered in intracellular spaces, was measured immunologically in a total of 187 samples of human seminal plasma. The values were between 1....