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Effects of cocoa powder and dark chocolate on LDL oxidative susceptibility and prostaglandin concentrations in humans
Cocoa powder dark chocolate LDL oxidation
2016/6/14
Flavonoids are polyphenolic compounds of plant
origin with antioxidant effects. Flavonoids inhibit LDL oxidation
and reduce thrombotic tendency in vitro. Little is known about
how cocoa powder and ...
Regional distribution of the prostaglandin E2 receptor EP1 in the rat brain: accumulation in Purkinje cells of the cerebellum
prostaglandin E2 EP1 prostanoid receptors rat brain cerebellum Purkinje cells cyclooxygenase neuroimmunology
2015/8/3
Prostaglandin E2 (PGE2), is a major prostanoid produced by the activity of cyclooxygenases (COX) in response to various physiological and pathological stimuli. PGE2 exerts its effects by activating fo...
Prostaglandin E₂ promotes recovery of hematopoietic stem and progenitor cells after radiation exposure
hematopoiesis radiomitigation radiation
2015/5/21
The hematopoietic system is highly proliferative, making hematopoietic stem and progenitor cells (HSPC) sensitive to radiation damage. Total body irradiation and chemotherapy, as well as the risk of r...
Defining the mechanism of prostaglandin E₂-enhanced hematopoietic stem and progenitor cell homing
Prostaglandin Homing HIF1-alpha
2015/5/21
Hematopoietic stem cell (HSC) transplantation is a lifesaving therapy for a number of hematological disorders. However, to be effective, transplanted HSCs must efficiently “home” to supportive niches ...
Ascorbic acid enhances the inhibitory effect of aspirin on neuronal cyclooxygenase-2-mediated prostaglandin E2 production
vitamin C cyclooxygenase-2 oxidative stress Alzheimer’s disease stroke reactive oxygen species neuroinflammation NSAIDs 8-isoprostanes prostaglandin E synthase
2015/8/3
Inhibition of neuronal cyclooxygenase-2 (COX-2) and hence prostaglandin E2 (PGE2) synthesis by non-steroidal anti-inflammatory drugs has been suggested to protect neuronal cells in a variety of pathop...
Lipocalin-Type Prostaglandin D Synthase and Egg White Cystatin React with IgE Antibodies from Children with Egg Allergy
cystatin food allergy hen's egg white LC-MS/MS lipocalin-type prostaglandin D synthase
2010/11/12
Background: Ovalbumin, ovomucoid, ovotransferrin, lysozyme, and ovomucin are known to be major allergens found in egg white. Egg white protein is composed of over 30 proteins; many of which have neith...
The Effects of Intrauterine Injection with Prostaglandin F2α,Arachidonic Acid and Phosphate Solution on the Eggshell Formation of Japanese Quail Hen
eggshell formation prostaglandin arachidonic acid phosphate quail
2009/7/31
Inhibitory effects of prostaglandin F2α, arachidonic acid and phosphate solution on the eggshell formation were investigated in Japanese quail. All injections were performed intrauterinely 8h before t...
Immuno-histochemical characteristics of necrotic area in the old-infarction area of human brain by using of antibodies against cystatin C, Cathepsin B, puromycin sensitive alanyl-aminopeptidase and Prostaglandin D2 synthase - A preliminary examination
Cystatin C Prostaglandin D2 synthase Brain infarction
2009/3/3
Figure 1: Old infarct area in the cerebellum from an individual (autopsy no.0636). Reticulation made by collagen-like fibers exist in the intact cortex by HE stain (1-A, top). Anti CC clearly sta...
Characterization of prostaglandin E receptor subtypes involved in the relaxation of rabbit penile corpus cavernosum smooth muscle
prostaglandin E receptor subtypes rabbit penile corpus cavernosum smooth muscle
2009/3/3
Prostaglandin E (PGE) induces the penile erection in the mammalians. Receptors for PGE were characterized to 4 different subtypes (EP1—4). The effects of agonists for EP1—4 receptors were studied on...
Influence of prostaglandin A2 and 2-methoxyestradiol on Bax and Bcl-2 expression levels in cervical carcinoma cells
prostaglandin A2 2-methoxyestradiol Bax Bcl-2 expression levels cervical carcinoma cells
2009/3/2
Proteins of the Bcl-2 family are key regulators of apoptosis. Bax can be regarded as pro-apoptotic, whereas Bcl-2 is perceived as anti-apoptotic. It has been proposed that an increased ratio of proa...
Influence of prostaglandin A2 on Bax, Bcl-2 and PCNA expression in MCF-7 cells
prostaglandin A2 Bcl-2 PCNA MCF-7 cells
2009/3/2
The effects of 20 μg/mL exogenous prostaglandin A2 (PGA2) were determined on Bax, Bcl-2 and proliferating cell nuclear antigen (PCNA) expression levels in MCF-7 cells. Flow cytometric analysis indic...
Prostaglandin facilitates afferent nerve activity via EP1 receptors during urinary bladder inflammation in rats
Prostaglandin facilitates EP1 receptors urinary bladder inflammation rats
2009/3/2
We examined the effects of loxoprofen, a cyclooxygenase inhibitor, and ONO-8711, an EP1-receptor antagonist, on afferent nerve activity during acetic acid (AA, 0.1% v/v)-induced inflammation of the ...
Indomethacin and oxaprozin lower seminal prostaglandin levels but do not influence sperm motion characteristics and serum hormones of young healthy men in a placebo-controlled double-blind trial
seminal prostaglandin levels sperm motion characteristics serum hormones young healthy men
2009/2/23
To evaluate the influence of indomethacin and oxaprozin on reproductive function in healthy young men, 34 volunteers with normal semen parameters were recruited. In a randomized double-blind design,...
Evidence for a role of cyclooxygenase（prostaglandin synthetase）and prostaglandins in the sperm acrosome reaction and fertilization
spermatozoa fertilization acrosome reaction cyclooxygenase prostaglandin inhibitor
2009/2/23
Three cyclooxygenase (prostaglandin synthetase) inhibitors, indomethacin, phenylbutazone, and oxyphenbutazone, decreased fertilization in vitro when mixed with capacitated mouse spermatozoa before a...
Prostaglandin dehydrogenase activity of rat and rabbit testicular tissues and accessory glands before and after castration
Prostaglandin dehydrogenase activity rat rabbit testicular tissues
2009/2/20
Rat reproductive tissues contained both 15-hydroxy-prostaglandin dehydrogenase (PGDH) and delta 13-reductase activities, while rabbit tissues exhibited only PGDH activity. In the rat, delta 13-reduc...