搜索结果: 1-15 共查到“ghrelin”相关记录79条 . 查询时间(0.093 秒)
分析连续性肾脏疗法(CRRT)治疗重症胰腺炎的疗效及对患者胰腺微循环指标和血清血清生长素(生长素释放肽),降钙素原(PCT)水平的影响。方法:回顾性分析我院经CRRT治疗(观察组)及经常规治疗(短期)的重症糖尿病炎患者各102例临床资料。记录临床症状缓解时间,并比较减少治疗前及治疗3d后视网膜微循环指标[血浆血流量(BF),血流体积(BV),血清学指标[Ghrelin,PCT,血栓素A2(TXA2...
分析血浆心血管营养素-1(CT-1),促生长激素释放激素(Ghrelin),脂蛋白相关性磷脂酶A2(Lp-PLA2)在冠心病中的临床价值。方法:选择我院2015年3月至2018年6月心内科收治的176例住院病人,其中43例,45例稳定型心绞痛(SAP),42例不稳定型心绞痛(UAP),46例急性心肌梗死(AMI) 。比较各组血浆CT-1,Ghrelin,Lp-PLA2水平,左室射血分数(LVVES...
探讨细胞外调节蛋白激酶1/2(extracellcular regulated protein kinase 1/2,ERK1/2)信号转导通路在ghrelin上调热休克蛋白70(heat shock protein 70,HSP70)表达及抑制氧化应激诱导PC12细胞凋亡中的作用。方法:采用硝普钠(sodium nitroprusside,SNP)诱导PC12细胞构建氧化应激损伤模型;实验分为S...
Ghrelin对糖尿病及其并发症的影响
糖尿病 胃饥饿素 糖尿病并发症
2020/1/21
促摄食激素胃饥饿素(Ghrelin)参与多种生物过程的调节,包括促进摄食、生长激素释放、能量平衡、胃动力和调节心血管动力等一系列生物学效应。糖尿病的传统发病机制包括胰岛素抵抗及胰岛β细胞功能受损,而Ghrelin促进胰岛α细胞分泌胰高血糖素的作用途径可能成为糖尿病发病机制的研究新热点。Ghrelin对糖尿病相关并发症的治疗有重要作用,具体表现在Ghrelin可能作为抗动脉粥样硬化的药物使用,同时有...
原发性高血压病人血浆HCY、Ghrelin和vWF表达水平与颈动脉硬化的相关性分析
原发性高血压 同型半胱氨酸 下丘脑生长激素促分泌素受体内源性配体 血管性血友病因子 颈动脉硬化 相关性
2020/7/14
探讨原发性高血压病人血浆同型半胱氨酸(HCY)、下丘脑生长激素促分泌素受体内源性配体(Ghrelin)、血管性血友病因子(vWF)表达水平与颈动脉硬化的相关性。方法选取2013年1月—2015年12月在本院住院治疗的原发性高血压病人150例为高血压组,同期健康体检人群150名为正常对照组,测定两组血浆HCY、Ghrelin和 vWF表达水平,同时比较两组颈动脉内膜中层厚度(cIMT)、颈动脉扩张性...
Ghrelin作为一种具有特殊功能的能量调控因子,在能量代谢平衡以及生殖调控研究中被广泛关注,然而其在小鼠性周期变化过程中发挥调控的机制尚不明确。本研究通过腹腔注射ghrelin研究其对小鼠性周期不同阶段采食量及血清中雌二醇浓度的影响,并运用免疫荧光技术鉴定了ghrelin与弓状核(arcuate nucleus,ARC)区域分布的α型雌二醇受体(estrogen receptor α,ERα)神...
Ghrelin在驯鹿器官内的表达及定位检测
Ghrelin 驯鹿 实时荧光定量PCR 免疫组化
2016/12/26
为了探索Ghrelin在驯鹿体内的表达及定位,采用实时荧光定量PCR(Real-time PCR)和免疫组织化学技术对其进行检测。Real-time PCR结果显示Ghrelin在所检测的17种器官中均有转录,在皱胃内的转录量最高,其次是胰、十二指肠、睾丸和食管,且转录量显著高于其他器官(P<0.05);免疫组化结果揭示Ghrelin的免疫阳性细胞在食管和皱胃内主要分布于黏膜层、黏膜下层和肌层;在...
llele frequency for c.335 A>C polymorphisms in porcine ghrelin/obestatin prepropeptide gene and association analysis with performance traits in various pig breeds
quantitative trait locus GHRL pigs polymorphism genetic marker
2015/10/9
The allelic frequency of c.335A>C polymorphisms in the porcine ghrelin/obestatin prepropeptide (GHRL) gene was surveyed among six pig breeds and two subspecies of wild boars. The c.335C was the most f...
Effect of in ovo ghrelin administration on subsequent serum insulin and glucose levels in newly-hatched chicks
chicken embryo ghrelin in ovo injection insulin
2015/6/9
Ghrelin is a regulatory peptide in glucose homeostasis in animal species. Its effect in the avian embryo is unclear. The aim of this study was to investigate the effects of in ovo ghrelin administrati...
The Effects of Exercise on Food Intake and Hunger: Relationship with Acylated Ghrelin and Leptin
Energy intake energy expenditure exercise hunger acylated ghrelin weight loss appetite
2015/5/7
This study investigated the effects of a long bout of aerobic exercise on hunger and energy intake and circulating levels of leptin and acylated ghrelin. Ten healthy male subjects undertook two, 4 h t...
Effects of Endurance Running and Dietary Fat on Circulating Ghrelin and Peptide YY
Exercise-induced anorexia gut peptides appetite regulation hunger exercise
2015/4/24
Ghrelin and peptide YY (PYY) are newly recognized gut peptides involved in appetite regulation. Plasma ghrelin concentrations are elevated in fasting and suppressed following a meal, while PYY concent...
Effects of Exercise in the Cold on Ghrelin, PYY, and Food Intake in Overweight Adults
WALKING AMBIENT TEMPERATURE ACYLATED GHRELIN TOTAL PYY ENERGY INTAKE
2017/4/14
Purpose: Exercise in cold water has been shown to simulate postexercise energy intake (EI) in normal-weight individuals. However, the effect of cold exercise on EI in overweight individuals has yet to...
饥饿素(ghrelin)在非酒精性脂肪肝病(NAFLD)中的研究进展
非酒精性脂肪肝病(NAFLD) 胰岛素抵抗 炎性反应 纤维化 肿瘤
2014/11/10
非酒精性脂肪肝病(non-alcoholic fatty liver disease,NAFLD)在肝脏疾病谱中占据日益重要的地位,其与胰岛素抵抗和氧化应激密切相关。饥饿素(ghrelin)作为一种新发现的从胃内提取的激素,是第一种生长激素促分泌素的内源性配体,能促进生长激素分泌,同时增强食欲,减少脂肪利用,维持能量正平衡,并在改善胰岛素抵抗、抑制炎性反应、抗纤维化和肿瘤等方面有一定作用,可能对N...
探讨由益生菌、谷氨酰胺、深海鱼油、肠内营养混悬液(能全力)组成的免疫微生态肠内营养对合并糖尿病的胃肠肿瘤患者肠耐受性和脑肠肽Ghrelin的影响。方法 92例合并糖尿病的胃肠肿瘤患者随机分为普通肠内营养组(对照组)和加入益生菌、谷氨酰胺、深海鱼油、能全力的免疫微生态肠内营养组(治疗组),各46例,两组均在手术中摆放鼻肠营养管,营养管放入空肠起始处,治疗组术后均给予免疫微生态营养,对照组给予能全力。...