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Much of the human genome is made of regulatory regions that control which genes are expressed at a given time within a cell. Those regulatory elements can be located near a target gene or up to 2 mill...
Despite the sheer number of genes that each human cell contains, these so-called “coding” DNA sequences comprise just 1 percent of our entire genome. The remaining 99 percent is made up of “non-coding...
We are pleased to announce the Cold Spring Harbor Asia conference on Systems Biology of Gene Regulation & Genome Editing which will be held in Suzhou, China, located approximately 60 miles west of Sha...
Inside every cell that makes up a diminutive fruit fly is a vast, dynamic network of information—the genome whose ~15,000 genes allow that cell to function In a study recently published as a Br...
LHX3 is a transcription factor important in pituitary and nervous system development. Patients with mutations in coding regions of the gene have combined pituitary hormone deficiency (CPHD) that cause...
Alzheimer’s disease (AD) is a neurological disorder defined by the presence of plaques comprised mostly of amyloid-β (Aβ), and neurofibrillary tangles consisting of hyperphosphorylated microtubule ass...
Based on the phosphorelay kinetics operative within BvgAS two component system we propose a mathematical model for signal transduction and differential gene regulation in Bordetella pertussis. To unde...
The inference, analysis and integration of networks of genes and products are fundamental goals of post-genomic research. Over the past few years several data- and knowledge-driven computational appro...
Two experiments were conducted to evaluate developmental gene expression of antimicrobial peptide PR-39 and effect of zinc oxide on gene regulation of PR-39 in piglets using semi-quantitative RT-PCR a...

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