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A Double-Blind Non-inferiority Clinical Study of Montelukast, a Cysteinyl Leukotriene Receptor 1 Antagonist, Compared with Pranlukast in Patients with Seasonal Allergic Rhinitis
comparative double blind study cysteinyl leukotriene receptor montelukast pranlukast seasonal allergic rhinitis
2010/11/17
Montelukast 5mg, 10mg once daily and the pranlukast 450mg/day showed significant improvements in the change from the baseline in the composite, daytime and nighttime nasal symptom scores, and the impr...
Therapeutic Effect of Montelukast, a Cysteinyl Leukotriene Receptor 1 Antagonist, on Japanese Patients with Seasonal Allergic Rhinitis
cysteinyl leukotriene receptor dose-response relationship montelukast rhinitis allergic seasonal
2010/11/17
Background: Secretion of nasal discharge was enhanced and airway-resistance in the nasal cavity was augmented, resulting in nasal congestion, when leukotrienes were administered to the nasal mucosa. T...
Population-based open-label clinical effectiveness assessment of the cysteinyl leukotriene receptor antagonist pranlukast
asthma pranlukast questionnaire symptom treatment
2010/11/26
Although the efficacy of cysteinyl leukotriene receptor antagonists in asthma therapy has been established through controlled clinical trials, there are no data concerning the effectiveness of their u...
Additive effect of cysteinyl leukotriene or thromboxane modifiers to inhaled corticosteroids in asthmatic patients
asthma corticosteroid cysteinyl leukotriene thromboxane
2010/11/22
Bronchial asthma is a chronic inflammatory disease of the conducting airways. Current asthma treatment guidelines recommend inhaled corticosteroids (ICS) as the first-line maintenance therapy for mild...
The Cysteinyl Leukotriene (CysLT) Pathway in Allergic Rhinitis
allergic rhinitis CysLT receptors CysLTs cytokines inflammation
2010/11/19
The cysteinyl leukotrienes (CysLTs), leukotriene C4(LTC4), leukotriene D4(LTD4 ) and leukotriene E4(LTE4 ) are released in response to specific allergen in nasal secretions from patients with active a...