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Correspondence of folate dietary intake and biomarker data
NHANES olate folic acid dietary assessment measurement error prevalence
2018/11/14
Background: Public health concerns with regard to both low and high folate status exist in the United States. Recent publications have questioned the utility of self-reported dietary intake data in re...
Dietary long-chain fatty acids and carbohydrate biomarker evaluation in a controlled feeding study in participants from the Women’s Health Initiative cohort
carbohydrate controlled feeding study dietary biomarker phospholipid fatty acids total fat
2018/11/14
Background: Biomarkers of macronutrient intake are lacking. Controlled human feeding studies that preserve the normal variation in nutrient and food consumption are necessary for the development and v...
Odd-chain fatty acids as a biomarker for dietary fiber intake: a novel pathway for endogenous production from propionate
soluble fiber fermentation pentadecanoic heptadecanoic liver long-chain fatty acid
2018/11/14
Background: The risk of type 2 diabetes is inversely correlated with plasma concentrations of odd-chain fatty acids [OCFAs; pentadecanoic acid (15:0) and heptadecanoic acid (17:0)], which are consider...
Biomarker-calibrated nutrient intake and healthy diet index associations with mortality risks among older and frail women from the Women’s Health Initiative
aging biomarker frailty inflammation mortality
2018/11/14
Background: Although studies to date have confirmed the association between nutrition and frailty, the impact of dietary intake and dietary patterns on survivorship in those with frailty is yet to be ...
Biomarker identified for likely aggressive,early stage breast cancer
Biomarker likely aggressive early stage breast cancer
2017/4/27
The one-size-fits-all approach to early stage breast cancer creates a paradox: Millions of dollars are spent on unnecessary surgeries and radiation to treat women with low-risk ‘in situ’ lesions, an e...
Dietary biomarker evaluation in a controlled feeding study in women from the Women’s Health Initiative cohort
carotenoids doubly labeled water energy fatty acids folate human feeding
2018/11/12
Background: Controlled human feeding studies are necessary for robust nutritional biomarker development and validation. Previous feeding studies have typically evaluated single nutrients and tested re...
The elephant in the room: using nutritional biomarker cutoffs to assess status
elephant nutritional biomarker cutoffs assess status
2018/12/19
The value of a nutritional biomarker rests in its ability to accurately assess the nutritional status of an individual or population. This has both clinical and public health implications. The correct...
Nanopolymer-modified protein array can pinpoint hard-to-find cancer biomarker
Nanopolymer-modified protein array cancer biomarker
2016/11/29
A Purdue University biochemist has developed a novel method for detecting certain types of proteins that serve as indicators for cancer and other diseases.
Glycoproteins are formed when sugars attach...
Salivary Biomarker Responses to Two Final Matches in Women’s Professional Football
Soccer hormones saliva T/C ratio RPE stress immune response
2016/7/7
The aim of this study was to examine the link between salivary concentrations of cortisol, testosterone, immunoglobulin A (IgA) and the rate of perceived exertion (RPE) as a measure of internal load a...
GlycA, a novel proinflammatory glycoprotein biomarker, and high-sensitivity C-reactive protein are inversely associated with sodium intake after controlling for adiposity: the Prevention of Renal and Vascular End-Stage Disease study
C-reactive protein diet GlycA glycoproteins inflammation nuclear magnetic resonance spectroscopy sodium excretion
2018/12/3
Background: The extent to which dietary sodium intake may confer alterations in the inflammatory status is unclear. GlycA is a novel proton nuclear magnetic resonance spectroscopy-measured biomarker o...
GlycA, a novel proinflammatory glycoprotein biomarker, and high-sensitivity C-reactive protein are inversely associated with sodium intake after controlling for adiposity: the Prevention of Renal and Vascular End-Stage Disease study
C-reactive protein diet GlycA glycoproteins inflammation nuclear magnetic resonance spectroscopy sodium excretion
2018/12/13
Background: The extent to which dietary sodium intake may confer alterations in the inflammatory status is unclear. GlycA is a novel proton nuclear magnetic resonance spectroscopy-measured biomarker o...
Developing Biomarker Arrays Predicting Sleep and Circadian-Coupled Risks to Health
Arrays Predicting Sleep Health
2017/3/10
The impact of advances in sleep and circadian sciences over
the last 20 years on medicine, health, and public safety has
been limited in part by the lack of availability of objective
tools capable ...
Sibios as a Framework for Biomarker Discovery Using Microarray Data
Microarray Data genomic data bioinformatics
2015/5/26
Decoding the human genome resulted in generating large amount of data that need to be analyzed and given a biological meaning. The field of Life Schiences is highly information driven. The genomic dat...
Biomarker Discovery in Early Stage Breast Cancer Using Proteomics Technologies
Biomarker Proteomics
2015/5/26
Among women in the United State, breast cancer is the most common cancer
diagnosed in women with approximately 200,000 new cases reported each year and the
second leading cause of cancer-related dea...
Concerns Regarding Hair Cortisol as a Biomarker of Chronic Stress in Exercise and Sport Science
Exercise hair cortisol physical activity review stress
2015/5/13
Hair cortisol has the potential to fill the methodological void of long-term cortisol assessment while becoming a widely accepted measure in biopsychology. This review critically examines the applicab...