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Effects of eight weeks of an alleged aromatase inhibiting nutritional supplement 6-OXO (androst-4-ene-3,6,17-trione) on serum hormone profiles and clinical safety markers in resistance-trained,eugonadal males
eight weeks aromatase inhibiting nutritional supplement 6-OXO serum hormone profiles clinical safety markers resistance-trained,eugonadal males
2015/7/13
The purpose of this study was to determine the effects of 6-OXO, a purported nutritional aromatase inhibitor, in a dose dependent manner on body composition, serum hormone levels, and clinical safety ...
Effect of aromatase inhibitor (fadrozole) on proliferation, estradiol production and telomerase activity in pig granulosa cells in vitro
granulosa cells aromatase inhibitor proliferation
2015/6/8
The objective of the present work was to study the effect of a nonsteroidal aromatase inhibitor (fadrozole) on proliferation, estradiol production, aromatase expression and telomerase activity (TA) in...
LH secretion and 17ββ-estradiol concentration in the blood plasma and hypothalamus of goldfish (Carassius auratus gibelio B.) and common carp (Cyprinus carpio L.) treated with fadrozole (aromatase inhibitor) and GnRH analogues
aromatase inhibitor LH estradiol goldfish carp ovulation
2015/6/4
Fadrozole – a non-steroidal aromatase inhibitor was applied to common carp and goldfish to examine its ability to potentiate the stimulatory action of GnRH analogues on LH secretion in vivo. The goal ...
Sex reversed chicks (Gallus domesticus) hatched from eggs treated with aromatase inhibitor YM511
aromatase inhibitor sex reversal chicken
2015/6/1
The objectives of this study were to assess post-hatch development of chickens treated in ovo with the aromatase inhibitor YM511. A total of 137 eggs coming from artificially inseminated hens were at ...
Effect of Estradiol and Nonylphenol on mRNA Expression of Estrogen Receptors α and β,and Cytochrome P450 Aromatase in the Gonad of Chicken Embryos
p-nonylphenol ERα ERβ P450arom endocrine disruptor
2009/7/31
Effects of estradiol-17β (E2) and p-nonylphenol (NP) on mRNA expression of estrogen receptor α (ERα), estrogen receptor β (ERβ) and cytochrome P450 aromatase (P450arom) were examined in the early stag...
Correlating Changes in Follicular VLDL Binding and Follicular Aromatase Activity in the Ovulation Cycle of the Laying Hen
Ovarian follicle VLDL-receptor Aromatase Ovulation cycle
2009/7/31
We examined whether very low-density lipoprotein receptors (VLDLR) on the oocyte membrane contributed to changes in VLDL uptake into the yolk by the ovarian follicle during the ovulation cycle of the ...
mRNA Expression of Cytochrome P450 17αhydroxylase,Cytochrome P450 Aromatase,Anti-Müllerian Hormone, Estrogen Receptor α,and Androgen Receptor in Developing Gonads of Japanese Quail
gene expression gonad Japanese quail
2009/7/30
Japanese quail (Coturnix coturnix japonica) is widely used in avian reproduction tests and avian sex reversal screening tests for evaluating adverse effects of endocrine disrupting chemicals (EDCs). H...
Effects of Aromatase Inhibitor (Fadrozole)-Induced Sex-Reversal on Gonadal Differentiation and mRNA Expression of P450arom,AMH and ERα in Embryos and Growth in Posthatching Quail
aromatase inhibitor P450arom mRNA quail gonad sex-reversal
2009/7/30
The present study was conducted to investigate (1) the effective day of treatment with Fadrozole, nonsteroidal aromatase inhibitor (AI), during incubation for sex reversal, (2) the mRNA expression of ...
Treatment of men with idiopathic oligozoospermic infertility using the aromatase inhibitor, testolactone. Results of a double-blinded, randomized, placebo-controlled trial with crossover
men idiopathic oligozoospermic infertility aromatase inhibitor testolactone
2009/2/23
The hypothesis that increased estradiol production may be the cause of impaired spermatogenesis in infertile men with idiopathic oligozoospermia was tested by administering the aromatase inhibitor...
Rat testicular germ cells and epididymal sperm contain active P450 aromatase
Estrogen testis epididymis
2009/2/17
Although testosterone is the principal sex steroid produced by the testis, estrogen is known to be produced by both Leydig and Sertoli cells during different developmental periods. Additionally, evide...
P450 aromatase messenger ribonucleic acid expression in male rat germ cells: detection by reverse transcription-polymerase chain reaction amplification
Germ cells spermatids P450 aromatase estrogen
2009/2/17
We have previously demonstrated that cytochrome P450 aromatase (P450arom) protein, an estrogen-synthesizing enzyme, is present and active in germ cells of the adult mouse testis. To establish that P...
Mouse epididymal sperm contain active P450 aromatase which decreases as sperm traverse the epididymis
Spermatozoa estrogen efferent ductules cytoplasmic droplet testicular excurrent ducts
2009/2/16
Recently we reported that mouse germ cells in the testis contain active P450 aromatase (P450arom), the enzyme that converts androgens to estrogens. This finding suggested that germ cells have the ...
Anti-androgen effects of the aromatase inhibitor, atamestane
Anti-androgen effects aromatase inhibitor atamestane
2009/2/13
Prostatic hyperplasia can be induced in both intact and castrated dogs and in intact cynomolgus monkeys by the administration of androgenic steroids. Estrogenic steroids potentiate this effect in ...
Atamestane, a new aromatase inhibitor for the management of benign prostatic hyperplasia
aromatase inhibitor management benign prostatic hyperplasia
2009/2/7
Atamestane is a new, competitive, and irreversible inhibitor of estrogen biosynthesis. Its pharmacologic action has been evaluated in mice, rats, rabbits, dogs, monkeys, and humans. In rats, atame...
Rationale for using aromatase inhibitors to manage benign prostatic hyperplasia. Experimental studies
aromatase inhibitors prostatic hyperplasia Experimental studies
2009/2/7
Today, human benign prostatic hyperplasia (BPH) is considered primarily to be a disease of the stroma, in which estrogens are thought to play a considerable causative or permissive role. The growi...