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Allele frequency in loci which control coat colours in Hucul horse population
Hucul horse population colours
2015/6/23
The objective of the study was to determine the frequency of alleles which produce coat colours
in Hucul horse population in Poland. The breed is included in the Global Strategy for Management of Fa...
The homozygosity index (HI) approach reveals high allele frequency for Wilson disease in the Sardinian population
Wilson disease genetic epidemiology consanguinity homozygosity index
2015/4/24
Wilson disease (WD) is an autosomal recessive disorder resulting in pathological progressive copper accumulation in liver and other tissues. The worldwide prevalence (P) is about 30/million, while in ...
Properties of neutrality tests based on allele frequency spectrum
Coalescent theory Site frequency spectrum Population genetics Statistical power Summary statistics
2010/11/9
One of the main necessities for population geneticists is the availability of statistical tools that enable to accept or reject the neutral Wright-Fisher model with high power.
Non-equilibrium allele frequency spectra via spectral methods
Non-equilibrium allele frequency spectra spectral methods
2010/11/24
A major challenge in the analysis of population genomics data consists of isolating signatures of natural selection from background noise caused by random drift and gene flow. Analyses of massive amou...