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cGAS-like receptors put a sting into the evolution of immune defence（图）
cGAS immune defence DNA 3'2'-cGAMP cGLR1 cGLR2
2021/8/10
Aspects of how immune defence processes evolved remain mysterious. Studies of the fly Drosophila melanogaster reveal previously unknown details of a defence pathway with echoes of, but key differences...
The first-ever molecular images of an olfactory receptor at work answer decades-old questions about odor recognition.
“Nuclear Receptors:From Structure to Disease”Symposium
Nuclear Receptors:From Structure to Disease Symposium
2017/11/27
On behalf of the organizing committee of the 8th Xiamen Winter Symposium, we would like to invite you to attend our conference. The theme is “Nuclear Receptors: From Structure to Disease”.The meeting ...
Receptors for Neuron Communication in Humans Vital for Reproduction in Mosses（图）
Receptors Neuron Communication Humans Vital Reproduction in Mosses
2017/9/1
A new study led by José Feijó, professor of cell biology and molecular genetics at the University of Maryland, revealed two previously unknown roles for glutamate receptor-like proteins in plants: con...
In Sex-Changing Fish,Male-Typical Sexual Behavior Associated With Elevated Expression Of Male Sex Hormone Receptors In Muscles
Sex-Changing Fish Male-Typical Sexual Behavior Male Sex Hormone Receptors Muscles
2017/7/21
Sex-changing fish exhibit differences in androgen receptor (AR) expression in muscles that are highly sensitive to androgens (male sex hormones) and essential for male courtship behavior, according to...
Inhibition of sweet chemosensory receptors alters insulin responses during glucose ingestion in healthy adults: a randomized crossover interventional study
sweet taste receptors lactisole glucose intolerance insulin saccharin artificial sweeteners OGTT modeling analysis
2018/11/13
Background: Glucose is a natural ligand for sweet taste receptors (STRs) that are expressed on the tongue and in the gastrointestinal tract. Whether STRs directly contribute to the regulation of gluco...
2017胆汁酸受体 Keystone Symposia（2017 Keystone Symposia on Bile Acid Receptors as Signal Integrators in Liver and Metabolism）
Liver and Metabolism Bile Acid Receptors
2017/1/17
The meeting will begin on Friday, March 3 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Tuesday, March 7 with a closing plenary session f...
Peroxisome proliferator-activated receptors: a family of lipid-activated transcription factors
differentiation fatty acids fatty acid synthase
2016/6/1
Peroxisome proliferator-activated receptors
(PPARs) are a family of nuclear transcription factors that belong
to the steroid receptor superfamily. This family of PPARs includes
PPARa, PPARd, PPARg1...
Opioid-induced hypophagia is mediated by 5-HT2c receptors in neonatal layer-type chicken
opioidergic 5-HTergic system food intake layer-type chicks
2015/10/9
Opioidergic and serotonergic (5-HTergic) systems have crucial role in central regulation of food intake. This study was designed to investigate the role of the opioidergic system and the interaction w...
Effects of vitamin D3 on expression of defensins, Toll-like receptors, and vitamin D receptor in liver, kidney, and spleen of Silky Fowl
vitamin D3 induction chicken avian β-defensins real-time PCR
2015/6/24
The expression of avian β-defensins (AvBDs), Toll-like receptors (TLRs), and vitamin D receptor (VDR) following in vivo vitamin D3 injection was studied. Healthy 90-day Silky Fowls were abdominally in...
Role of Adenosine A1 Receptors in Native Coronary Atherosclerosis, In-stent Stenosis, and Coronary Blood Flow Regulation in Metabolic Syndrome and Exercise
Aldosterone Coronary heart disease Exercise
2015/5/22
Adenosine is widely thought to elicit coronary vasodilation and attenuate smooth muscle cell (SMC) proliferation, thereby providing cardioprotection. We cloned the porcine adenosine A1 receptor (A1R) ...
Sphingosine 1-phosphate enhances excitability of sensory neurons through sphingosine 1-phosphate receptors 1 and/or 3
sphingosine 1-phosphate S1P excitability sensory neurons G protein-coupled receptors
2015/5/21
Sphingosine 1-phosphate (S1P) is a bioactive sphingolipid that has proven to be an important signaling molecule both as an extracellular primary messenger and as an intracellular second messenger. Ext...
ELUCIDATING MECHANISMS THAT LEAD TO PERSISTENT ANXIETY-LIKE BEHAVIOR IN RATS FOLLOWING REPEATED ACTIVATION OF CORTICOTROPIN-RELEASING FACTOR RECEPTORS IN THE BASOLATERAL AMYGDALA
anxiety corticotropin-releasing factor somatostatin amygdala basolateral amygdala
2015/5/21
Anxiety disorders are estimated to impact 1 in 4 individuals within their lifetime. For some individuals, repeated episodes of the stress response leads to pathological anxiety and depression. The str...
Effect of polychlorinated biphenyls on the secretion of oxytocin from luteal and granulosa cells in cow: possible involvement of glucocorticoid receptors
polychlorinated biphenyls oxytocin glucocorticoid receptors ovary cow
2015/3/5
Polychlorinated biphenyls (PCBs) stimulate oxytocin secretion from bovine granulosa and luteal cells. Since oxytocin on the one hand is released from ovarian cells by cortisol and on the other hand PC...
Alpha adrenergic receptors are involved in the contractile activity of neuropeptide Y in the porcine isolated ovarian artery
neuropeptide Y α-adrenergic agonists α-adrenergic antagonists norepinephrine porcine ovarian artery blood pressure
2015/1/27
The objective of this study was to determine whether α-adrenergic receptors are involved in the contractile activity of neuropeptide Y (NPY) in the porcine isolated ovarian artery collected from immat...