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中国科学院遗传与发育生物学研究所陆发隆研究组应邀在Trends in Biochemical Sciences撰写题为“Beyond simple tails: poly(A) tail-mediated RNA epigenetic regulation”的综述文章（图）
陆发隆 真核生物 基因
2024/8/11
2024年7月14日，Trends in Biochemical Sciences杂志在线发表了中国科学院遗传与发育生物学研究所陆发隆研究组撰写的题为“Beyond simple tails: poly(A) tail-mediated RNA epigenetic regulation”的综述论文(DOI:10.1016/j.tibs.2024.06.013)。该论文总结了近年来关于RNA po...
Green plasticizers derived from epoxidized soybean oil for poly (vinyl chloride): Continuous synthesis and evaluation in PVC films
Green plasticizers Micro-flow system Continuous synthesis Mechanical performance
2024/1/12
In this paper, the epoxidation process and the ring-opening reaction were integrated to develop an efficient bio-based plasticizer in a continuous flow mode. Four novel plasticizers based on epoxidize...
High-strength and self-healable poly (acrylic acid) /chitosan hydrogel with organic-inorganic hydrogen bonding networks
Self-healing hydrogel Hydrogen bonding Organic-inorganic
2023/12/8
Bentonite?is a natural clay mineral with high cationic exchange properties and plays an important role in organic-inorganic composite hydrogels. We report an organic-inorganic cross-linked self-healin...
卵子向胚胎转变过程是人类繁衍后代的最重要的生命过程之一。在该过程中，人类胚胎8-细胞时期合子基因组激活之前，卵子和胚胎中DNA是不转录的。因此，卵子向胚胎转变过程主要受卵子中储存的母源mRNA调控。2023年1月17日，Nature Structural & Molecular Biology发表了题为Remodeling of maternal mRNA through poly(A) tail...
卵子向胚胎转变过程是人类繁衍后代的最重要的生命过程之一。在该过程中，人类胚胎8-细胞时期合子基因组激活之前，卵子和胚胎中DNA是不转录的。因此，卵子向胚胎转变过程主要受卵子中储存的母源mRNA调控。2023年1月17日，《Nature Structural & Molecular Biology》期刊发表了题为《Remodeling of maternal mRNA through poly(A)...
南方科技大学生命科学学院翟继先团队绘制植物多组织mRNA poly(A)尾长度图谱
南方科技大学生命科学学院 翟继先 Nature Plants 植物多组织 mRNA poly(A)尾长度 图谱
2022/10/19
近日，南方科技大学生命科学学院植物与食品研究所翟继先副教授团队在Nature Plants在线发表了题为“An atlas of plant full-length RNA reveals tissue-specific and monocots-dicots conserved regulation of poly(A) tail length”的研究论文。该研究建立了包含拟南芥7个不同组织以及...
浙江大学生命科学研究院2021年5月29日范衡宇实验室揭示MAPK级联通路通过激活poly(A)聚合酶促进卵母细胞减数分裂的机制（图）
范衡宇 联通路通过激活 poly(A)聚合酶 卵母细胞 生殖治疗
2022/10/25
雌性哺乳动物在出生以后，卵母细胞的细胞周期停滞在减数第一次分裂前期，直到排卵前夕才在促性腺激素的刺激下恢复减数分裂，经不对称分裂排出极体，等待受精。卵母细胞的减数分裂成熟是受精成功的关键，也常常是辅助生殖治疗中的卡脖子问题。异常的染色体分离会导致胚胎非整倍性，造成早期流产或后代遗传疾病。
Biocompatible green tea extract-stabilised zinc nanoparticles encapsulated by poly(butyl-2-cyanoacrylate) with control release profile and antioxidative capacity
biocompatible green tea butyl-2-cyanoacrylate GT-Zn-NPs
2023/4/20
Green tea extract-stabilised Zn nanoparticles (GT-Zn NPs) encapsulated by poly(butyl-2-cyanoacrylate) (PBCA@GT-Zn NPs) were developed for control release of Zn. The crucial parameters, concentrations ...
Crystallization kinetics and morphology of small concentrations of cellulose nanofibrils (CNFs) and cellulose nanocrystals (CNCs) melt-compounded into poly(lactic acid) (PLA) with plasticizer
Poly(lactic acid) Nucleation Nanocellulose Avrami kinetics Crystallization
2024/2/27
In the present study, very small concentrations of CNCs and CNFs were melt-compounded into PLA using a solvent-free process where poly(ethylene glycol) (PEG) was used to disperse the nanoparticles in ...
Rosin‐derived poly(vinyl chloride) plasticizer: Synthesis, structure, and properties
rosin-based polyacid esters Synthesis structure properties
2024/2/29
In this work, rosin‐based plasticizer was synthesized by Diels–Alder (DA) and esterification. First, the maleopimaric acid (RT) was obtained by DA between the double bond of rosin and maleic anhydride...
中国科学院遗传与发育生物学研究所陆发隆研究组开发PAIso-seq方法揭示RNA poly(A)尾巴内部广泛存在其他碱基修饰（图）
中国科学院遗传与发育生物学研究所 陆发隆 PAIso-seq方法 RNA poly(A) 尾巴内部 碱基修饰
2019/11/29
RNA poly(A)尾巴是成熟的mRNA和lncRNA的重要组成部分，对RNA稳定性和翻译起着重要的调控作用。然而目前的poly(A)尾巴检测技术仍然非常有限。2019年11月22日，中国科学院遗传与发育生物学研究所陆发隆研究组在Nature Communications发表题为Poly(A) inclusive RNA isoform sequencing (PAIso-seq) reveal...
3D Printing of Poly(propylene fumarate) Oligomers: Evaluation of Resin Viscosity, Printing Characteristics and Mechanical Properties
3D Printing Poly(propylene fumarate) Oligomers Resin Viscosity
2024/2/29
Complex three-dimensional (3D) pore geometries, useful for tissue engineering scaffolds, can be fabricated via photo-crosslinking of resorbable poly(propylene fumarate) (PPF) resins using stereolithog...
Synthesis and Evaluation of Soy Fatty Acid Ester Estolides as Bioplasticizers in Poly(Vinyl Chloride)
Estolide Plasticizer PVC Soybean Oil Fatty Acid Esters
2024/3/4
Plasticizers are nonvolatile organic liquids that impart flexibility to polymers. Due to environmental, health, and safety reasons, the industry is looking for bioplasticizers to replace petroleum-der...
Soybean Oil Modified Bio-based Poly(vinyl alcohol)s via Ring-Opening Polymerization
Biodegradable properties Epoxidized soybean oil Modification Poly(vinyl alcohol)
2024/3/4
In this paper, a simple method to modify the poly(vinyl alcohol) (PVA) through ring-opening reaction of epoxidized soybean oil (ESBO), catalyzed by hydrochloric acid is reported. The effect of ESBO lo...
