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近日,合成生物学领域国际知名期刊《代谢工程》(Metabolic Engineering)在线发表了武汉大学药学院、中南医院药学研究院、泰康生命医学研究中心邓子新院士团队陈文青教授课题组关于“搭建大肠杆菌平台,智造核苷类医药中间体”的重要研究成果。武汉大学为该论文的第一署名单位,博士研究生于乐、高耀杰为共同第一作者,陈文青教授为通讯作者。
Woody plant species represent an invaluable reserve of biochemical diversity to which metabolic engineering can be applied to satisfy the need for commodity and specialty chemicals, pharmaceuticals, a...
Plants live in fixed locations and have evolved adaptation mechanisms that integrate multiple responses to various environmental signals. Among the different components of these response pathways, rec...
2023年10月30日植物生物学论坛—292:Harnessing plant metabolic diversity for food and health applications。
Although type 2C protein phosphatases (PP2Cs) have been demonstrated to play important roles in regulating plant development and various stress responses, their specific roles in rice abiotic stress t...
The circadian rhythm regulates the daily cycles of various physiological activities. Accumulating evidences revealed that circadian rhythm plays an important role in regulating metabolic homeostasis, ...
The physiological and metabolic difffferences between shoot tips and roots of tea plants are signifificant, and understanding them is required for improvement of tea quality and plant growth. A high-q...
高效的代谢途径是细胞工厂生产的关键,然而同源或异源多基因途径的不平衡和低效,会导致潜在的有毒中间体的积累。CRISPR技术可以提供更加简单、高效、低成本的代谢途径改造与优化方法。 中科院天津工业生物技术研究所张学礼研究员带领的微生物代谢工程团队和毕昌昊研究员带领的合成生物技术研究团队,受邀在Metabolic Engineering发表基于CRISPR的代谢工程调控前沿综述。该文章介绍了传统的代谢...
An enzyme can be used as a metabolically responsive "switch" that decreases tumor growth, according to a new study. The findings are published in the journal Nature.By restricting the dietary ami...
Background: Induction of nonshivering thermogenesis can be used to influence energy balance to prevent or even treat obesity. The pungent component of mustard, allyl-isothiocyanate (AITC), activates t...
近日,中国地质大学生物地质与环境地质国家重点实验室李平团队在国际著名期刊《Water Research》(IF 6.942)上在线发表了论文——高砷地下水中微生物群落功能结构及其代谢潜能分析(Analysis of the functional gene structure and metabolic potential of microbial community in high arsenic...
Background: Evidence suggests that fat-free mass and resting metabolic rate (RMR), but not fat mass, are strong predictors of energy intake (EI). However, body composition and RMR do not explain the e...
Background: In research settings that use metabolic balance studies (MBSs) of stable adult patients with short bowel syndrome, intestinal failure (IF) and dependence on parenteral support (PS) have be...
Background: In research settings that use metabolic balance studies (MBSs) of stable adult patients with short bowel syndrome, intestinal failure (IF) and dependence on parenteral support (PS) have be...
Background: Recent years have seen strong tendencies toward high-protein diets. However, the implications of higher protein intake, especially during developmentally sensitive periods, are poorly unde...

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