搜索结果: 1-15 共查到“Cell Cycle”相关记录23条 . 查询时间(0.171 秒)
Transcription factor-pathway co-expression analysis reveals cooperation between SP1 and ESR1 on dysregulating cell cycle arrest in non-hyperdiploid multiple myeloma
coexpression cell cycle arrest multiple myeloma hyperdiploid
2016/1/25
Multiple myeloma is a hematological cancer of plasma B cells and remains incurable. Two major subtypes of myeloma, hyperdiploid MM (HMM) and non-hyperdiploid MM (NHMM), have distinct chromosomal alter...
Transcription factor-pathway co-expression analysis reveals cooperation between SP1 and ESR1 on dysregulating cell cycle arrest in non-hyperdiploid multiple myeloma
coexpression cell cycle arrest multiple myeloma hyperdiploid
2016/1/20
Multiple myeloma is a hematological cancer of plasma B cells and remains incurable. Two major subtypes of myeloma, hyperdiploid MM (HMM) and non-hyperdiploid MM (NHMM), have distinct chromosomal alter...
Assessment of transcript and protein levels contributing to cell cycle control and gap junction connections in morphologically variable groups of porcine cumulus-oocyte complexes
pig oocyte connexins
2015/4/7
Oocytes and somatic cumulus cells are connected by an extensive network of gap junctions. These connections contribute in a major way to oocyte maturation and developmental competence. Cumulus-oocyte ...
{\it CSE1}, an essential yeast gene required for cell cycle progression, encodes a nuclear transport factor
Brewing yeast genes chromosomes genes cell cycle and protein nuclear proteins
2014/12/11
CSE1, an essential Saccharomyces cerevisiae gene was initially isolated in a screen for genes important for accurate chromosome segregation. cse1 mutants have pleiotropic phenotypes including defects ...
The role of cell cycle progression and cyclin -dependent kinase 2 in thymocyte negative selection
T cells and thymus cells thymus self antigen cells
2014/12/11
Autoreactive, immature T cells (thymocytes) are deleted from the thymus during development by the process of negative selection. This mechanism occurs when the thymocyte, T cell receptor (TCR) recogni...
Proteolytic Regulation of CtrA, the Master Regulator of Cell Cycle in Caulobacter crescentus
Caulobacter proteolysis CtrA SciP
2014/12/9
Cell cycle progression in Caulobacter crescentus depends on the master regulator, CtrA. During the transition from swarmer to stalk cell (G1 to S phase), CtrA is degraded by the AAA+ protease ClpXP an...
A phenomenological model for the dynamics of cell cycle in responding to X-rays
DNA repair G2 arrest G1 arrest Computational model Ionizing radiation
2015/9/6
To establish a model to predict the cell-cycle process in response to ionizing radiation.Methods Human choroidal malignant melanoma 92-1 cells were used and the cell cycle distribution of cells was an...
A new framework for identifying combinatorial regulation of transcription factors: a case study of the yeast cell cycle
framework identifying combinatorial regulation transcription factors yeast cell cycle
2010/11/15
By integrating heterogeneous functional genomic datasets, we have developed a new framework for detecting combinatorial control of gene expression, which includes estimating transcription factor activ...
XPC DNA REPAIR PROTEIN REGULATION IN THE CONTEXT OF THE G1/S CELL CYCLE CHECKPOINT
XPC DNA repair retinoblastoma protein cell cycle
2015/5/21
DNA is subject to various types of damage that can impair cellular function or cause cell death. DNA damage blocks normal cellular processes such as replication and transcription and can have catastro...
Effects of high-dose major components in oral disinfectants on the cell cycle and apoptosis in primary human gingival fibroblasts in vitro
Cell cycle and apoptosis Human gingival fibroblasts Oral disinfectants
2010/11/26
We evaluated the effects of high-dose major components in oral disinfectants on oral cells from the standpoints of the cell cycle and apoptosis. We examined the viability and cell cycle of human gingi...
G2 checkpoint abrogation as a cancer specific,cell cycle disruption
Cell Cycle G2 checkpoint DNA damage Chemo-sensitization Oncogenesis
2009/7/15
The majority of cancer cells are thought to have accumulated the necessary mutations for oncogenesis as a result of disrupting the cell cycle G1 checkpoint, leading to the replication of damaged DNA. ...
High hydrostatic pressure and chromate-induced effects on cell cycle kinetics
cell cycle kinetic chromate Glioma animal
2009/7/14
Cell cycle kinetics was studied using the quenching of 33258 Hoechst fluorescence by bromodeoxyuridine incorporation to investigate effects of high pressure on the toxicity of a welding fume component...
Flow Cytometric Analysis of the Effects of Methotrexate and Vepesid on the HEp-2 Cell Cycle
Cell cycle Methotrexate Vepesid HEp-2 cell flow cytometer
2009/6/29
Objective: To determine the mechanism of action of Methotrexate and Vepesid on the HEp-2 cells isolated from human laryngeal cancer cells morphologically and flow cytometrically (G1, G2, S and PI). Ma...
Cell Cycle Regulation through Ubiquitin/Proteasome-Mediated Proteolysis in Plants
CDK cyclin 26S proteasome
2009/6/10
Understanding the mechanism of cell cycle control in plants is important for agricultural technology enabling enhancement of growth rate and then crop yield. Progression of the cell cycle requires the...
Effects of tea constituents on cell cycle progression of human leukemia U937 cells
tea constituents cell cycle progression human leukemia U937 cells
2009/3/2
Tea and tea constituents are known to induce apoptosis in a variety of cancerous cells, suggesting their beneficial effects as chemopreventive agents. Previous studies have shown that low molecular ...