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三名著名的病毒学家致函世界卫生组织(WHO)总干事,要求采取更强有力的措施来根除HTLV-1病毒---一种逆转录病毒,是导致成人白血病的原因之一。在他们的致函信中,澳大利亚昆士兰大学的Fabiola Martin、美国马里兰大学医学院的Yutaka Tagaya和Robert Gallo提出如今是国际社会对这种病毒及其所造成的危害给予更多关注的时候了。这封致函信获得其他58名病毒学家的签名。特约撰...
浙江大学生命科学研究院夏总平实验室在PLoS Pathogens发表论文揭示HTLV-1病毒蛋白Tax激活宿主NF-κB信号通路的机制(图)
浙江大学生命科学研究院夏总平实验室 PLoS Pathogens HTLV-1病毒蛋白Tax激活宿主NF-κB信号通路
2016/4/20
2016年4月15日,浙江大学生命科学研究院夏总平实验室在PLoS Pathogens刊物 (影响因子为7.562)上在线发表题为“HTLV-1 Tax Functions as a Ubiquitin E3 Ligase for Direct IKK Activation via Synthesis of Mixed-Linkage Polyubiquitin Chains”的研究论文。人T细胞...
The imprint of the Slave Trade in an African American population: mitochondrial DNA, Y chromosome and HTLV-1 analysis in the Noir Marron of French Guiana
the Slave Trade African American population mitochondrial DNA Y chromosome HTLV-1 analysis Noir Marron French Guiana
2015/4/9
Background: Retracing the genetic histories of the descendant populations of the Slave Trade (16th-19th centuries) is particularly challenging due to the diversity of African ethnic groups involved an...
Background: HTLV-1 infection is endemic in Mashhad, Northeast of Iran. This study was designed to assess the epidemiology of HTLV-1 and potential risk factors in Neyshabour, Northeastern Iran.
Serologic Activity against HTLV-I in Patients with Primary Sjögren’s Syndrome in Mashhad,an Endemic Area
Sjö gren’s syndrome Human T cell Leukemia Virus type I (HTLV-I) Northeastern Iran
2015/9/22
Background: There are accumulating evidences that Human T cell Leukemia Virus type I (HTLV-I) plays a part in the development of Sjögren's Syndrome (SS). This virus is endemic in some areas of th...
Evaluation of HTLV-1 in Human Subgingival Plaque of Seropositive Patients
Human T-lymphotropic virus Dental Plaque Polymerase Chain Reaction
2009/12/17
Objective: The aim of this study was to investigate the existence of human T-lymphotropic virus type 1 (HTLV-1) in subgingival plaque of HTLV-1 seropositive pa-tients.
Materials and Methods: A total ...
A Further Insight into the Origin of Human T-Lymphotropic Virus Type 1 (HTLV-1) in Japan, Based on the Genotyping of ABCC11
Human T-Lymphotropic Virus Type 1 (HTLV-1) Japan
2010/12/10
A Further Insight into the Origin of Human T-Lymphotropic Virus Type 1 (HTLV-1) in Japan, Based on the Genotyping of ABCC11.
HTLV-I Infection: Virus structure, Immune Response to the Virus and Genetic Association Studies in HTLV-I-Infected Individuals
CTL response Cytokine gene polymorphism HAM/TSP HTLV-I MHC
2010/2/5
Although the structure of human T lymphoptropic virus type I (HTLV-I) has been known well, the function of some proteins encoded by HTLV-I PX region is not fully understood. Furthermore, the responses...
大公报港大破解HTLV-1病毒致白血病机制
白血病;病毒感染;抗癌药物
2021/12/2
香港大学医学院成功破解由病毒感染引致人类T细胞白血病病毒1型(HTLV-1),的机制,有助开发新一代抗癌药物。这种白血病在香港比较少见,过去五、六年约有六至七宗死亡个案,其中半数是在日本经性接触感染病毒。
CHANGES IN HTLV-I POSITIVE RATES AMONG PREGNANT WOMEN IN OKINAWA PRIOR TO THE EFFECTS OF MEASURES INTRODUCED TO PREVENT VERTICAL TRANSMISSION THROUGH BREAST MILK FEEDING
HTLV-I Okinawa pregnancy
2010/12/10
Objectives: Human T cell leukemia virus type-I (HTLV-I) is a causative agent of human T-cell leukemia and HTLV-I associated myelopathy (HAM/TSP). HTLV-I carriers are often infected vertically, especia...