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提供了由哺乳动物YAP蛋白或具有转录控制活性的片段的融合蛋白的与细胞全能性和转录激活结构域相关的基因编码的蛋白、编码核苷酸序列、表达载体及其组合物,以及使用该融合蛋白诱导多能干细胞的方法。
本发明提供了一种hnRNP A2*蛋白质,编码该蛋白的核酸及用途。所述蛋白含有蛋白,蛋白质片段或蛋白质的类似物或衍生物的氨基酸序列如SEQ ID NO。1。本发明hnRNP A2*蛋白质能主动解开端粒G-四,结合最小结合位点,在3′端粒的尾端,露出五个核苷酸可配合端粒酶RNA模板和促进端粒延伸端粒酶的作用下,从而保持细胞的分裂潜能。
2024年5月9日,万建民院士团队与北京大学贾桂芳团队合作在Molecular Plant发表了题为The RNA binding protein EHD6 recruits the m6A reader YTH07 and sequesters OsCOL4mRNA into phase-separated ribonucleoprotein condensates to promote ric...
Currently, synthetic polymers are extensively used due to their superior properties such as inexpensive and ease of processing. They are non-degradable and create pollution in the environment. There i...
Calcium-dependent protein kinases (CDPKs), as an important calcium sensor in plants, are widely involved in the signal transmission process of growth and development, pathogen defense response and bio...
Actin binding proteins and transcription factors are essential in regulating plant root hair growth in response to various environmental stresses;however, the interaction between these two factors in ...
Ankyrin (ANK) repeat-containing proteins occur widely in prokaryotes, eukaryotes, and even in some viruses and play a critical role in plant growth and development, as well as the response to biotic a...
Hydrogen sulfide (H2S) is a signaling molecule that regulates plant hormone and stress responses. The phytohormone abscisic acid (ABA) plays important role during plant adaptation to unfavorable envir...
Protein kinase dynamics play key roles in regulation of cell differentiation, growth, development and in diverse cell signaling networks. Protein kinase sensors enable visualization of protein kinase ...
G-proteins are molecular on–off switches that are involved in transmitting a variety of extracellular signals to their intracellular targets. In animal and yeast systems, the switch property is encode...
NAC transcription factors play crucial roles in plant resistance to a variety of adverse circumstances. Here, we characterized a NAC transcription factor PwNAC1 from Picea wilsonii and subcellular loc...
棉花是一种重要的工业作物,逐渐转向在干旱地区种植。然而,参与植物响应各种胁迫的Tubby-like protein,TULP在棉花中很少被报道。本研究通过调节气孔运动,展示了GhTULP30对植物耐受干旱胁迫的改进。GhTULP30在酵母中的异源表达显著提高了其抗盐和干旱耐受性。GhTULP30的过表达使得拟南芥种子在种子萌发期间更加抵御干旱和盐胁迫,并且在干旱胁迫条件下提高了该植物的气孔关闭速度...
本研究对艾克曼棉、斯蒂芬氏棉和一个陆地棉野生种系进行测序,解析了棉花多倍化及适应性进化过程中广泛存在的基因组结构变异,阐述了棉花生物多样性和棉花驯化的遗传基础;发现编码磷酸肽结合蛋白的基因结构变异可能与棉花纤维长度调控有关,烯酰辅酶Aδ异构酶3和RAP2-7可通过调节植物激素提高棉花非生物胁迫耐受性。研究结果揭示了棉花多倍化过程中的适应性进化机制,为棉花抗性和纤维品质遗传改良提供了宝贵的遗传材料。
Improving the sensitivity of protein-protein interaction detection and protein structure probing is a principal challenge in cross-linking mass spectrometry (XL-MS) data analysis. In this talk, we pro...
Many of the biological materials that researchers are most interested in studying, including those associated with major diseases, don’t lend themselves to the conventional methods that researchers ty...

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