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Leptin is a peptide that is strongly correlated with adiposity and is a potential determinant of obesity and its complications.
Since first reported less than a decade ago (1), leptin has been a topic of considerable study. The variation in serum or plasma leptin concentrations has been described according to sex, age, measu...
Although it is known that plasma leptin concentrations correlate with the amount of adipose tissue in the body, little information is available on the long-term effects on leptin concentrations of ...
Plasma leptin in humans is subject to both longand short-term regulation; it correlates with indexes of body fat that can only change slowly. However, short-term fasting causes large and rapid decr...
Little is known about the effects of physical training on plasma leptin concentrations in children.
Background: Formula feeding or overweight in infancy may increase the later risk of obesity, but the mechanisms involved are uncertain. Because obesity is associated with high leptin concentratio...
Background: Obesity in Prader-Willi syndrome (PWS) may be related to abnormalities in the adipocyte-leptin-hypothalamic pathway and may be exacerbated by reductions in the resting metabolic rate ...
Background: Leptin, the product of the obese (ob) gene, is a regulator of food intake and energy metabolism. Immunoreactive leptin was detected recently in breast milk and it has been hypothesized ...
Background: Leptin is thought to represent a peripheral signal involved in the regulation of energy balance. Its action has been studied in animals and obese subjects. Little is known about leptin’s...
Background: Leptin is produced in proportion to body fat mass and can act on the brain to induce satiety and regulate adipose tissue mass; factors other than adipose tissue mass may influence circu...

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