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Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2
SARS-CoV-2 human ACE2 transgenic mouse COVID-19 pneumonia
2020/6/11
COVID-19 has spread worldwide since 2019 and is now a severe threat to public health. We previously identified the causative agent as a novel SARS-related coronavirus (SARS-CoV-2) that uses human angi...
Ovariectomy increases squamous metaplasia of the uterine horns and survival of SENCAR mice fed a vitamin A–deficient diet
ovariectomy survival vitamin A deficiency
2016/6/1
Retinoic acid is necessary for the growth and differentiation
of organisms and exerts its molecular actions by
binding to specific nuclear receptors that belong to the thyroidsteroid
hormone recept...
Ultrastructural and morphometrical changes of mice ovaries following experimentally induced copper poisoning
Copper poisoning Electron microscopy Morphometry Ovary Mice
2015/9/28
Background: Copper (Cu) is an essential trace element involved in normal reproduction but its overexposure may produce some detrimental effects. The aim of this study was to investigate the effects of...
Nifedipine in the treatment of liver toxicity induced by Acetaminophen overdose in mice
Liver toxicity Nifedipine liver
2009/12/30
Acetaminophen is an analgesic and antipyretic drug, which is widely used by public and poisoning with this drug, is common. One of the most important adverse effects of acetaminophen poisoning is cent...
Moderate beer consumption does not change early or mature atherosclerosis in mice
beer mature atherosclerosis
2008/4/23
Although the consumption of wine in particular has been associated with a lower risk of atherothrombotic cardiovascular disease, systematic reviews differ as to the relative protective effect of beer,...
Contribution of CD4+ or CD8+ T cell subsets in the induction of asthma in C57BL/6 mice
asthma C57BL 6 mice CD4+ T cell CD8+ T cell influenza virus
2010/11/22
Background: Respiratory viral infections are known to be a risk factor for the exacerbation of asthma. In a model of asthma with influenza A virus infection, dendritic cells play an important role dur...
Effect of Storage on the Infectivity of Vampirolepis Nana var. Nana Eggs to Swiss Albino Mice
Vampirolepis nana Cestode Swiss albino mice
2010/2/3
Vampirolepis nana is the most common cestode in humans especially children. Domestic mice and rats can serve as definitive hosts for V. nana. Confusion exists over the species status and host-specific...
Role of the small intestine in postpartum weight retention in mice
lactation weight retention D-glucose
2017/1/5
The objective of the study was to determine whether pregnancy-related adaptive increases in intestinal nutrient transport are retained after parturition and therefore contribute to postpartum weight g...
Overexpression of arginase I in enterocytes of transgenic mice elicits a selective arginine deficiency and affects skin,muscle,and lymphoid development
Arginine arginase I Peyer’s patch myocyte hair immunonutrition enterocytes transgenic mice
2016/12/19
Background: Arginine is required for the detoxification of ammonia and the synthesis of proteins, nitric oxide, agmatine, creatine, and polyamines, and it may promote lymphocyte function. In suck...
Green tea extract decreases muscle necrosis in mdx mice and protects against reactive oxygen species
Green tea muscular dystrophy reactive oxygen species antioxidant prevention muscle necrosis mdx mice dystrophin X-linked congenital disease
2016/12/17
Background: Duchenne muscular dystrophy is a severe X-linked congenital disorder characterized by lethal muscle wasting caused by the absence of the structural protein dystrophin.Objective: ...
Incorporation of deuterated RRR- or all-rac-α-tocopherol in plasma and tissues of α-tocopherol transfer protein–null mice
Vitamin E deuterium-labeled α-tocopherol α-TTP knockout mice mass spectrometry vitamin E requirement liver brain
2016/12/17
Background: Most vitamin E supplements contain synthetic all-rac-α-tocopherol [2,5,7,8-tetramethyl-2RS-(4′RS,8′RS,12-trimethyltridecyl)-6-chromanol] with 8 stereoisomers; only 1 is identical...
Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E–deficient mice
Pomegranate juice flavonoids lipid peroxidation LDL HDL macrophage paraoxonase platelet, atherosclerosis antioxidants men atherosclerotic apolipoprotein E–deficient mice
2016/6/7
Background: Dietary supplementation with nutrients rich in
antioxidants is associated with inhibition of atherogenic modifications
to LDL, macrophage foam cell formation, and atherosclerosis.
Pomeg...