搜索结果: 1-5 共查到“口腔医学 RANKL”相关记录5条 . 查询时间(0.093 秒)
目的: 探讨RNAi技术体外沉默大鼠骨髓间充质干细胞(BMSCs)OPG基因提高RANKL/OPG比例的可行性。方法: 设立空载组(空慢病毒载体转染BMSCs)和OPG沉默组(含OPG基因干扰片段的慢病毒载体转染BMSCs),RT-PCR检测OPG及RANKL的mRNA表达变化,Western blot检测OPG及RANKL的蛋白表达变化。结果: 与空载组比较,OPG沉默组OPG的mRNA和蛋白表...
Titanium Surface Roughness Accelerates RANKL-dependent Differentiation in the Osteoclast Precursor Cell Line,RAW264.7
Titanium Osteoclast Implant
2009/9/14
The present study was a molecular analysis of the initial differentiation of osteoclast precursor RAW264.7 cells on titanium specimens. RAW264.7 cell line was cultured on titanium specimens of which t...
Regulation of the Response of the Adult Rat Condyle to Intermaxillary Asymmetric Force by the RANKL-OPG System
Traction Temporomandibular joint Osteoclasts RANKL Osteoprotegerin Bone turnover marker
2010/3/5
Objective: To test the hypothesis that the RANKL-OPG system in the subchondral bone of adult rat condyles does not vary in response to different values of intermaxillary asymmetrical forces.
Materi...
持续静压力对人牙周膜细胞RANKL mRNA表达的影响
压力 牙周膜细胞 细胞核因子KB受体活化因子配体
2009/6/25
持续静压力对人牙周膜细胞RANKL mRNA表达的影响。
OPG/RANKL/RANK系统及其临床应用
骨保护素 核因子κB受体活化因子配体 核因子κB受体活化因子
2009/4/22
人OPG,RANK和RANKL是3个肿瘤坏死因子家族新成员,主要存在于人的骨髓及其他少数组织中。2000年美国骨与矿物质研究协会对其给予了标准化命名,并统称为OPG/RANKL/RANK系统。作为破骨细胞形成、分化和骨吸收调节的关键调节物,OPG/RANKL/RANK系统在骨质疏松、骨硬化病、类风湿性关节炎、骨肿瘤、Paget’s病、牙周炎及正畸牙移动等临床疾病的发病机制及治疗方面均取得了较大...