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Effects of KF19514, a Phosphodiesterase 4 and 1 Inhibitor, on Bronchial Inflammation and Remodeling in a Murine Model of Chronic Asthma
airway hyperresponsiveness airway remodeling asthma murine model PDE inhibitor
2010/11/16
Background: Phosphodiesterase 4 selective inhibitor may prevent airway inflammation and remodeling.
Objective: The aim of this study was to investigate the effects of KF19514, a phosphodiesterase 4 a...
Remodeling of Airway Walls in Fatal Asthmatics Decreases Lymphatic Distribution; Beyond Thickening of Airway Smooth Muscle Layers
airway-remodeling bronchial asthma lymphangiogenesis lymphatic capillary mucosal edema
2010/11/17
These results indicate that distribution of lymphatics were decreased in the airway walls of fatal asthmatics which contained muscle bundles and fibro-connective tissues both of which were augmented i...
Mechanisms of Airway Remodeling in Asthma
airway remodeling goblet cells inflammation smooth muscle subepithelial fibrosis
2010/11/18
Asthma is a chronic inflammatory disease characterized by reversible airflow limitation and airway hyperresponsiveness. Persistent inflammation in airway tissues may lead to structural changes known a...
专著信息
书名
Study of Traditional Chinese Medicine in Intervening Vascular Remodeling after Percutaneous Trasluminal Coronary Angioplasty
语种
英文
撰写或编译
作者
Lu Xiaoyan,Xu Hao,Shi Dazhuo
第一作者单位
出版社
Chin J Integ...
期刊信息
篇名
Effect of drugs on mRNA expression of voltage-gated potassium channels myocardial remodeling by charonic L-thyroxine adminstration in rats
语种
英文
撰写或编译
撰写
作者
Fang-Zhi Fang,Zi-Zhen Wang,De-Zai D...
Airway Remodeling and Airway Smooth Muscle in Asthma
airway hyperresponsiveness hyperplasia hypertrophy in vitro in vivo
2010/11/19
Airway remodeling in asthma has been recognized as structural changes of airways such as smooth muscle hypertrophy (an increase in size of airway smooth muscle cells) and hyperplasia (an increase in t...