搜索结果: 1-13 共查到“临床医学 airway inflammation”相关记录13条 . 查询时间(0.062 秒)
Inhibitory effect of calotropis gigantea extract on ovalbumin-induced airway inflammation and arachidonic acid induced inflammation in a murine model of asthma
arachidonic acid Calotropis gigantea ovalbumin
2015/7/21
The root of Calotropis gigantea has been reported as a traditional folkloric medicine in treatment of asthma in the Indian literature. Root contain α-and β-amyrin are reported to possess anti-lipoxyge...
The Effect of Omega-3 Fatty Acids on Airway Inflammation, Hyperpnea-Induced Bronchoconstriction, and Airway Smooth Muscle Contractility in Asthma
Asthma Bronchoconstriction Fish Oil
2015/5/22
Asthma, a chronic inflammatory disease of the airways, affects nearly 25 million Americans. The vast majority of these patients suffer from exercise-induced bronchoconstriction (EIB), a complication o...
Amphiregulin Is Not Essential for Ovalbumin-Induced Acute Airway Inflammation in Mice
amphiregulin asthma EGF IgE mast cells
2010/11/12
Background: The number of amphiregulin (AR)-positive mast cells in the bronchial mucosa and the levels of AR in sputum from asthmatic patients have been reported to be increased. In addition, AR can p...
Enhanced Goblet Cell Hyperplasia in HDC Knockout Mice with Allergic Airway Inflammation
airway remodeling asthma Gob-5 MUC5AC TNF-α
2010/11/16
The number of eosinophils in BALF increased in both the sensitized wild-type mice and Hdc-/- mice with OVA inhalation. In addition, the numbers of alveolar macrophages and lymphocytes in BALF increase...
How Early Do Airway Inflammation and Remodeling Occur?
Asthma child eosinophil neutrophil pre-school wheeze
2010/11/17
Eosinophilic airway inflammation and structural airway changes are present in school age asthmatics. When these changes occur, and their relationship, are controversial. Some structural airway changes...
Effect of Procaterol, a β2 Selective Adrenergic Receptor Agonist, on Airway Inflammation and Hyperresponsiveness
airway hyperresponsiveness allergic inflammation eosinophil murine model β2 adrenergic receptor agonist
2010/11/18
Background: β-agonists are frequently used as bronchodilators for asthma as not only a reliever but also a controller, and their utility has increased with the development of long-acting β2 selective ...
The Distinctive Effects of Acute and Chronic Psychological Stress on Airway Inflammation in a Murine Model of Allergic Asthma
airway inflammation bronchial asthma opioid psychological stress μ-opioid receptor
2010/11/18
In BALB/c mice, but not in C57BL/6 mice, the number of total cells, eosinophils and lymphocytes in the acute stress group were significantly decreased compared with those in the non-acute stress group...
Role of nitric oxide in airway inflammation and hyperresponsiveness in bronchial asthma
arginine epithelial cells inhibitory nonadrenergic non-cholinergic nerve L-NAME peroxynitrate
2010/11/26
Nitric oxide (NO) is produced within the airways and has a variety of actions on the airway function. Nitric oxide is a potent bronchodilator, and NO released from airway epithelial cells and inhibito...
Effect of a leukotriene receptor antagonist, pranlukast hydrate, on airway inflammation and airway hyperresponsiveness in patients with moderate to severe asthma
airway hyperresponsiveness airway inflammation asthma eosinophils leukotriene leukotriene receptor antagonist
2010/11/25
Asthma is characterized by chronic airway inflammation and the recruitment of inflammatory cells, typically eosinophils and lymphocytes, into the airway. Although several chemical mediators are releas...
Effect of short-course steroid treatment for airway inflammation in patients with asthma
asthma bronchial biopsy corticosteroid eosinophil lymphocyte
2010/11/24
Background: The effect of short-term corticosteroid treatment for airway inflammation in asthma is not well known. To investigate this effect, we analyzed bronchial mucosal biopsy samples.
Methods: W...
Attenuation of allergic airway inflammation and associated pulmonary functions by mycobacterial antigens is independent of IgE in a mouse model of asthma
airway hyperresponsiveness asthma Bacillus Calmette-Guérin eosinophils IgE Mycobacterium vaccae
2010/11/24
Neither BCG nor M. vaccae were able to attenuate the EAR, yet both were able to abrogate the parameters used to evaluate the LAR. Interestingly, in neither case were serum or OVA-specific IgE levels r...
Reduced Serum Antibody Production and Acute Airway Inflammation in Interleukin 6-deficient Mice Challenged with Ovalbumin
animal asthma cytokine eosinophil IL-6
2010/11/19
Background: IL-6 is a unique cytokine that has pro- and anti-inflammatory property. The purpose of this study was to clarify the role of IL-6 in the allergic airway inflammation.
Methods: We challeng...
Increased Levels of CTGF mRNA Expression in a Murine Model of Allergic Airway Inflammation
asthma collagen remodeling subepithelial fibrosis TGF-β
2010/11/19
Numbers of eosinophils and TGF-β1 concentration increased markedly in BALF on the 7th day and 14th day after inhalation challenge with OVA. Hydroxyproline content in lung tissue increased significantl...