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TARC和MDC在日本血吸虫感染小鼠Th2应答及肝纤维化中的作用
日本血吸虫 Th2应答 趋化因子 肝脏纤维化
2013/11/27
目的探讨胸腺活化调节趋化因子（thymus activation regulated chemokine，TARC）和巨噬细胞来源的趋化因子（macrophagederived chemokine，MDC）对日本血吸虫感染宿主Th2应答及肝脏纤维化的影响。方法建立日本血吸虫感染小鼠模型，取肠系膜淋巴结及肝脏，胞内细胞因子染色法和ELISA法检测Th2应答；实时荧光定量RTPCR法检测TARC和...
The Effect of Suplatast Tosilate on TARC Production in Peripheral Blood Mononuclear Cells and TARC Plasma Levels
allergic rhinitis chemokines suplatast tosilate TARC
2010/11/22
Suplatast tosilate significantly reduced TARC production by PBMCs. TARC mRNA was also suppressed in a concentration dependent manner. However, suplatast tosilate did not inhibit the expression of CCR-...