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Every day, billions of red blood cells pass through the spleen, an organ that is responsible for filtering out old or damaged blood cells. This task is made more difficult when the blood cells are mis...
Pancreas on a chip(图)     Pancreas  chip       2019/10/18
By combining two powerful technologies, scientists are taking diabetes research to a new level. In a study led by Harvard University's Kevin Kit Parker, microfluidics and human insulin-producing beta ...
2019年8月27日,北京大学分子医学研究所,北京大学-清华大学生命科学联合中心研究员何爱彬研究组在Molecular Cell杂志在线发表题为“CoBATCH for high-throughput single-cell epigenomic profiling”的文章,报道了一种新的具有普适性、易操作、高通量和高质量的单细胞ChIP-seq技术,并将其命名为CoBATCH(combinato...
近日,法国巴黎文理研究大学等科研人员在Nature Genetics上发表了题为“High-throughput single-cell ChIP-seq identifies heterogeneity of chromatin states in breast cancer”的文章,利用高通量单细胞ChIP-seq确定了乳腺癌染色质状态的异质性。
Imagine wearing a device that continuously analyzes your sweat or blood for different types of biomarkers, such as proteins that show you may have breast cancer or lung cancer. Rutgers engineers have ...
“微流控芯片与组织工程研讨会(Workshop on Microfluidic Chip and Tissue Engineering)”将于2017年6月9日-11日在六朝古都南京榴园宾馆召开。本次会议由东南大学主办,由生物科学与医学工程学院和生物电子学国家重点实验室承办。本次会议诚挚邀请国内外各大院校、科研院所、生物医学工程相关企业等单位从事生物医学工程研究的知名专家、学者、企业家进行深入交流...
Harvard University researchers have made the first entirely 3D-printed organ-on-a-chip with integrated sensing. Built by a fully automated, digital manufacturing procedure, the 3D-printed heart-on-a-...
WEST LAFAYETTE, Ind. – Researchers have developed a chip capable of simulating a tumor's "microenvironment" and plan to use the new system to test the effectiveness of nanoparticles and drugs that tar...
Researchers at Penn State have demonstrated an acoustofluidic pump powered by a piezoelectric transducer about the size of a quarter. This reliable, inexpensive, programmable pump is a crucial feature...
本文采用3H-TdR标记的放射自显影术,秋水仙碱阻断法和显微分光技术,研究了CHIP对小鼠艾氏腹水癌细胞动力学的影响。实验发现:CHIP(30 mg/kg)对呈指数生长和坪区生长的肿瘤细胞具有抑制增殖的效应,并可见对G0细胞的损伤作用,对S期和M期细胞未见特异性杀伤。CHIP还能引起细胞周期进程的广泛延缓,尤其以G1-S阻缓最为明显。上述结果表明CHIP为周期非特异性药物。
目的:建立RNA多聚酶Ⅱ-染色质免疫沉淀-引物延伸-飞行时间质谱技术(PolⅡ-ChIP-PE-MS),并利用该方法检测SNP等位特异磷酸化PolⅡ结合量,为活体状态下研究疾病关联基因SNP的功能研究提供一种高通量的研究手段.方法:采用PCR-RFLP方法对HepG2细胞印迹基因SNRPN(仅父源等位基因表达)基因组DNA和cDNA进行基因分型,利用PolⅡ CTD末端Ser5特异性抗体进行染色质...
UEHARA, L. A.; BUTTON, C.; DAVIDS, K. The effects of focus of attention instructions on novices learning soccer chip. Brazilian Journal of Biomotricity, v. 2, n. 1, p. 63-77, 2008. Research has sug...
Microdialysis is a sampling technique based on controlling the mass transfer rate of different-sized molecules across a semipermeable membrane. Because the dialysis process has minimal effects on the ...
本研究观察了雌二醇和Anordiol(一种有激动剂活性的抗雌激素药物)对未成年雌性大鼠子宫水通道(AQP-CHIP)基因表达的调控作用。我们根据两种大鼠AQP-CHIP水通道cDNA保守序列设计合成了一对寡核苷酸引物,用于扩增从大鼠子宫总RNA反转录而成的cDNA片段。给未成年大鼠用单剂量的雌二醇(40μg·kg-1)9h后,AQP-CHIPmRNA的表达量显著增加。雌二醇和Anordiol的最低...

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