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A phenomenological model for the dynamics of cell cycle in responding to X-rays
DNA repair G2 arrest G1 arrest Computational model Ionizing radiation
2015/9/6
To establish a model to predict the cell-cycle process in response to ionizing radiation.Methods Human choroidal malignant melanoma 92-1 cells were used and the cell cycle distribution of cells was an...
Effects of high-dose major components in oral disinfectants on the cell cycle and apoptosis in primary human gingival fibroblasts in vitro
Cell cycle and apoptosis Human gingival fibroblasts Oral disinfectants
2010/11/26
We evaluated the effects of high-dose major components in oral disinfectants on oral cells from the standpoints of the cell cycle and apoptosis. We examined the viability and cell cycle of human gingi...
G2 checkpoint abrogation as a cancer specific,cell cycle disruption
Cell Cycle G2 checkpoint DNA damage Chemo-sensitization Oncogenesis
2009/7/15
The majority of cancer cells are thought to have accumulated the necessary mutations for oncogenesis as a result of disrupting the cell cycle G1 checkpoint, leading to the replication of damaged DNA. ...
High hydrostatic pressure and chromate-induced effects on cell cycle kinetics
cell cycle kinetic chromate Glioma animal
2009/7/14
Cell cycle kinetics was studied using the quenching of 33258 Hoechst fluorescence by bromodeoxyuridine incorporation to investigate effects of high pressure on the toxicity of a welding fume component...
Flow Cytometric Analysis of the Effects of Methotrexate and Vepesid on the HEp-2 Cell Cycle
Cell cycle Methotrexate Vepesid HEp-2 cell flow cytometer
2009/6/29
Objective: To determine the mechanism of action of Methotrexate and Vepesid on the HEp-2 cells isolated from human laryngeal cancer cells morphologically and flow cytometrically (G1, G2, S and PI). Ma...
Effects of tea constituents on cell cycle progression of human leukemia U937 cells
tea constituents cell cycle progression human leukemia U937 cells
2009/3/2
Tea and tea constituents are known to induce apoptosis in a variety of cancerous cells, suggesting their beneficial effects as chemopreventive agents. Previous studies have shown that low molecular ...
Induction of cell cycle arrest and apoptosis in JAR trophoblast by antimalarial drugs
cell cycle arrest apoptosis JAR trophoblast antimalarial drugs
2009/3/2
Chloroquine, quinine, artemisinin, and pyrimethamine are generally considered safe drugs for treatment of malaria during pregnancy; however, high doses of these drugs are detrimental with adverse ou...