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Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease
Structure-based design antiviral drug candidates targeting SARS-CoV-2 protease
2020/6/12
SARS-CoV-2 is the etiological agent responsible for the global COVID-19 outbreak. The main protease (Mpro) of SARS-CoV-2 is a key enzyme that plays a pivotal role in mediating viral replication and tr...
Structure-based Design Used as Tool for Engineering Deimmunized Biotherapeutics（图）
Design Used as Tool Deimmunized Biotherapeutics
2015/3/4
In the first experimental use of algorithms that employ structure-based molecular modeling to optimize deimmunized drug candidates, Karl Griswold, PhD, and co-investigator Christopher Bailey-Kellogg, ...