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Gene Expression Profiles of BAD and Bcl-xL in the CA1 Region of the Hippocampus Following Global Ischemic/Reperfusion and FK-506 Administration
Ischemic/Reperfusion Real-Time RT-PCR Hippocampus Tacrolimus Bcl-xL Gene BAD
2015/12/29
Background: The hippocampus is a tiny nub in the mammalian brain that is involved in forming, organizing, and storing memories. Global cerebral ischemia (GCI) and reperfusion induced apoptosis lead to...
Effect of Exercise on Learning, Memory and Levels of Epinephrine in Rats’ Hippocampus
Exercise memory hippocampus epinephrine
2015/3/11
The aim of the present study was to investigate effect of exercise on learning and memory, long-term potentiation and levels of epinephrine in the rat hippocampus. Treadmill trained (one hour at 17 m·...
Effect of Exercise on Diabetes-Induced Oxidative Stress in the Rat Hippocampus
Oxidation Stress Diabetes Treadmill Exercise Apoptosis Hippocampus
2015/9/25
Background: Oxidative stress forms the foundation for the induction of multiple cellular pathways which can lead to the complications of diabetes mellitus that the most debilitating ones are diseases ...
Soft-diet Feeding Inhibits Adult Neurogenesis in Hippocampus of Mice
Mastication Neurogenesis Neurotrophin
2010/1/21
Our previous study showed that mice fed on a soft diet after weaning had reduced levels of brain-derived neurotrophic factor (BDNF) protein in the hippocampus after 3 months of age compared with mice ...
Soft-diet Feeding Inhibits Adult Neurogenesis in Hippocampus of Mice
Mastication Neurogenesis Neurotrophin
2010/12/1
Our previous study showed that mice fed on a soft diet after weaning had reduced levels of brain-derived neurotrophic factor (BDNF) protein in the hippocampus after 3 months of age compared with mice ...
Superoxide dismutase responds to hyperoxia in rat hippocampus
Atmospheric Pressure Hippocampus enzymology Hyperbaric Oxygenation animal rat
2009/6/4
The brain's anti-oxidant response to highly elevated oxygen (O2) partial pressures is poorly understood. In this study we hypothesized that hyperbaric O2 (HBO2) would stimulate superoxide dismutase (S...
Hyperbaric oxygenation therapy enhances the protective effect of moderate hypothermia against forebrain ischemia in the gerbil hippocampus
Hyperbaric Oxygenation neurological HYPOTHERMIA ischemia animal gerbil brain hippocampus
2009/6/2
Moderate hypothermia may have a beneficial effect on the neurological outcome. However, ischemic deterioration such as brain swelling during rewarming has been reported as a notable complication after...
Inhibitory Modulation of Glutamatergic Neuron Activity by Zinc in the Hippocampus
zinc glutamate mossy fiber hippocampus calcium exocytosis synaptic plasticity
2009/3/23
Zinc exists in high densities in the giant boutons of hippocampal mossy fibers. Zinc decreases extracellular glutamate concentration in the hippocampus, suggesting inhibitory modulation of glutamaterg...
Involvement of Zinc in Neuronal Death in the Hippocampus
zinc glutamate excitotoxicity hippocampus calcium
2009/3/16
Zinc is released with glutamate from neuron terminals in the hippocampus. Zinc may serve as a negative-feedback factor of presynaptic activity and negatively modulate postsynaptic calcium mobilization...
Effects of Soft-diet Feeding on BDNF Expression in Hippocampus of Mice
Mastication Synaptogenesis Neurotrophin
2010/12/1
Our previous study showed that mice fed a soft diet after weaning had reduced synaptic connections in the hippocampal formation and impaired spatial learning ability after 3 months of age. We hypothes...