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Synthesis of the Amide Derivatives of 3-[1-(3-Pyridazinyl)-5-phenyl-1H-pyrazole-3-yl]propanoic Acids as Potential Analgesic Compounds
Pyridazine pyrazole analgesic writhing
2010/4/8
A series of structurally diverse amide derivatives of 3-[1-(3-pyridazinyl)-5-phenyl-1H-pyrazole-3-yl]propanoic acids were prepared and tested for their in vivo analgesic activity using an acetic acid...
Synthesis of Some New 1-Acylthiosemicarbazides and 1,2,4-Triazol-5-Thiones, and Their Analgesic and Anti-Inflammatory Activities
2-Benzothiazolinone thiosemicarbazide 1,2,4-triazol-5-thione analgesic and anti-inflammatory activity
2010/4/16
We synthesized new 1-[3-(2-oxobenzothiazolin-3-yl)propanoyl]-4- substituted-thiosemicarbazides and their corresponding cyclized 3-[2-(2-oxobenzothiazoline-3-yl)ethyl]-4-substituted-1,2,4-triazol-5-thi...
Synthesis of Some New Pyridylethylated Benzoxa(Thia)zolinones with Analgesic Activitiy
2-Benzoxazolinone 2-Benzothiazolinone Acylation Pyridylethyl Analgesic activity
2010/4/21
Eighteen new 3-[2-(2-/4-pyridyl)ethyl]benzoxazolinone (benzothiazolinone) derivatives were synthesized by reacting 2-/4-vinylpyridine and appropriate benzoxazolinones and benzothiazolinones. The analg...
Synthesis and Analgesic and Anti-Inflammatory Activity of New Pyridazinones
6-Oxo-3,5-diphenylpyridazine synthesis spectral analysis analgesic anti-inflammatory
2010/4/21
A new series of 2-(6-oxo-3,5-diphenyl-6H-pyridazin-1-yl)- acetamides and 3-[6-oxo-3,5-diphenyl-6H-pyridazin-1-yl)-propanamides were synthesized and evaluated in terms of their analgesic and anti-infla...
Synthesis of New 4-(5-Chloro-2-oxo-3H-benzoxazol-3-yl)butanamide Derivatives and Their Analgesic and Anti-Inflammatory Properties
2-Oxo-3H-benzoxazole butanamide analgesic anti-inflammatory COX-1 COX-2
2010/4/21
In this preliminary screening study for developing potent analgesic and anti-inflammatory compounds, eight new 4-(5-chloro-2-oxo-3H-benzoxazol-3-yl)butanamide derivatives were synthesized and screened...