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双核Pt(Ⅳ)配合物与Guanosine-5′-Monophosphate和Glutathione反应的核磁共振光谱研究(英文)
抗肿瘤试剂 双核铂(Ⅳ)配合物 DNA Guanosine-5′-Monophosphate(5′-GMP) Glutathione(GSH)
2008/3/20
合成了一个新型的双核Pt(Ⅳ)配合物{[cis-Pt(NH3)2Cl(OH)2]2(4,4′-methylenedianiline)}(NO3)2(化合物1)及相应的 15N标记化合物{[cis-Pt( 15NH3)2Cl(OH)2]2 (4,4′-methylenedianiline)}(NO3)2(化合物 15N-1)。利用 1H NMR和ESMS进行了结构表征,化合物 15N-1的2D[ 1...
Rapid Complexometric Determination of Mercury(II) Using Glutathione as a Selective Demasking Reagent
Complexometry Demasking reagent EDTA titration Glutathione Mercury determination
2010/4/20
A simple, rapid and selective complexometric method is proposed for the determination of mercury(II) in the presence of associated metal ions. Mercury(II) is first complexed with an excess of EDTA and...
Evidence for a Hybrid Ping Pong-Semirandom Mechanism for Human Jejunal Glutathione Disulfide Reductase
Glutathione disulfide reductase ping pong-semirandom mechanism human jejunum
2010/6/27
Initial rate versus substrate concentration, [S], profiles (at pH 7.4, 37oC) for human jejunal glutathione disulfide reductase indicated partial substrate inhibition by GSSG at fixed [NADPH] \le 40 m ...