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Model Verification and the Likelihood Principle
Model verification Mis-specification testing Hypothesis testing Likelihood principle Sufficiency principle Evidence
2016/6/13
The likelihood principle (LP) is typically understood as a constraint on any measure of evidence arising from a statistical experiment. It is not sufficiently often noted, however, that the LP assumes...
Representation as a Process of Model-Building:A Case from Economics
Representation Model-Building Static Idea of Representation Dynamic Idea of Representation Nancy Cartwright Robert Sudgen International Trade Theory
2016/6/12
What does it mean to say that a theory represents the targeted phenomenon that it aims to explain? Our interpretation of “representation” is closely related to the methodological position that we woul...
Diagrams as Locality Aids for Explanation and Model Construction in Cell Biology
cell biology diagram explanation locality aid model construction
2016/5/30
Using as case studies two early diagrams that represent mechanisms of the cell division cycle, we aim to extend prior philosophical analyses of the roles of diagrams in scientific reasoning, and speci...
The structure of idealization in biological theories:the case of the Wright-Fisher model
idealization theory biology possible worlds
2016/5/30
In this paper we present a new framework of idealization in biology. We characterize idealizations as a network of counterfactual and hypothetical conditionals that can exhibit different “degrees of c...
What consent model is ethically justifiable in cancer population research?
cancer population consent model
2017/4/10
The important role that explicit informed consent plays in the conduct of research cannot be denied. Inhumane medical research has prompted over many decades the articulation of guidelines, legislatio...
Leibniz's Model Of Creation And His Doctrine Of Substance
Leibniz's Model Creation Substance
2009/12/3
The subject of creation has long been recognized as central to Leibniz's philosophy.1
In general, the tendency has been to understand Leibniz's view of the creation of the
universe as the actualizat...
A biobank management model applicable to biomedical research
biomedical research biobank management
2008/11/12
Background
The work of Research Ethics Boards (REBs), especially when involving genetics research and biobanks, has become more challenging with the growth of biotechnology and biomedical research. S...
DNA databanks and consent: A suggested policy option involving an authorization model
DNA databanks consent
2008/11/7
Background
Genetic databases are becoming increasingly common as a means of determining the relationship between lifestyle, environmental exposures and genetic diseases. These databases rely on large...