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Causal explanation beyond the gene: manipulation and causality in epigenetics
causation explanation intervention epigenetics methodology observational studies causalidad explicación intervención epigenética metodología estudios observacionales
2016/5/27
This paper deals with the interrelationship between causal explanation and methodology in a relatively young discipline in biology: epigenetics. Based on cases from molecular and ecological epigenetic...
Re-Examining the Gene in Personalized Genomics
Direct-to-Consumer Genetic Testing DTC Genes Genetic Determinism Science Communication Public understanding of genetics
2016/5/27
Personalized Genomics companies (PG; also called ‘Direct-to-Consumer Genetics’) are businesses marketing genetic testing to consumers over the Internet. While much has been written about these new bus...
Gene
Karola Stotz Gene
2008/4/14
The historian Raphael Falk has described the gene as a ‘concept in tension’ (Falk 2000) – an idea pulled this way and that by the differing demands of different kinds of biological work. Several autho...
An alternative to Kitcher's theory of conceptual progress and his account of the change of the gene concept
concepts conceptual change gene concept
2008/4/10
The present paper discusses Kitcher’s framework for studying conceptual change and progress. Kitcher’s core notion of reference potential is hard to apply to concrete cases. In addition, an account of...